{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:35:20Z","timestamp":1761006920220,"version":"build-2065373602"},"reference-count":20,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2010,9,5]],"date-time":"2010-09-05T00:00:00Z","timestamp":1283644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Magnetic Reson in Chemistry"],"published-print":{"date-parts":[[2010,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In this article, we describe the characteristic <jats:sup>15<\/jats:sup>N chemical shifts of isatin oxime ethers and their isomer nitrone. These oxime ethers and nitrones are the alkylation reaction products of isatin oximes. In our study, the <jats:sup>15<\/jats:sup>N chemical shifts observed in these oxime ethers were in the 402\u2013408 (or 22\u201328) ppm range, although those for their corresponding nitrone series were in the 280\u2013320 (or \u2212100 to \u221260) ppm range. This remarkable difference in <jats:sup>15<\/jats:sup>N NMR chemical shift values could potentially be used to determine the <jats:italic>O<\/jats:italic>\u2010 <jats:italic>versus<\/jats:italic> <jats:italic>N<\/jats:italic>\u2010alkylation of oximes, even when only one isomer is available. In this paper, the differences in <jats:sup>15<\/jats:sup>N NMR chemical shifts serve as the basis for a discussion about how to distinguish both regioisomers derived from the oximes alkylation. Copyright \u00a9 2010 John Wiley &amp; Sons, Ltd.<\/jats:p>","DOI":"10.1002\/mrc.2680","type":"journal-article","created":{"date-parts":[[2010,9,6]],"date-time":"2010-09-06T01:17:30Z","timestamp":1283735850000},"page":"873-876","source":"Crossref","is-referenced-by-count":6,"title":["<sup>15<\/sup>N chemical shifts of a series of isatin oxime ethers and their corresponding nitrone isomers"],"prefix":"10.1002","volume":"48","author":[{"given":"Xiaohong","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaohua Stella","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ny","family":"Sin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian L.","family":"Venables","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikram","family":"Roongta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,9,5]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1081\/SCC-200034750"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.5570330326"},{"key":"e_1_2_6_3_3","doi-asserted-by":"publisher","DOI":"10.1002\/poc.1167"},{"key":"e_1_2_6_3_4","doi-asserted-by":"publisher","DOI":"10.1002\/mrc.1076"},{"key":"e_1_2_6_3_5","doi-asserted-by":"publisher","DOI":"10.1021\/jo961386s"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.84"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.2.179"},{"key":"e_1_2_6_5_3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043951"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja00866a027"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo01288a002"},{"volume-title":"NMR Spectroscopy of the Non\u2010metallic Elements","year":"1997","author":"Berger S.","key":"e_1_2_6_8_2"},{"volume-title":"Nitrogen\u201015 Nuclear Magnetic Resonance Spectroscopy","year":"1979","author":"Levy G. 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