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H\/D exchange reactions were performed using a chloroform\/D\n                    <jats:sub>2<\/jats:sub>\n                    O, 1:2 molar ratio, vigorously stirred, at room temperature. One mole of KOH was dissolved in D\n                    <jats:sub>2<\/jats:sub>\n                    O fraction and catalytic complexes from 0.002 to 0.05 mmol were dissolved in chloroform. The H\/D exchange reactions were monitored using\n                    <jats:sup>13<\/jats:sup>\n                    C nuclear magnetic resonance sequences without proton decoupling. The reaction using 0.01 mmol of compound A reached approximately 55% of H\/D conversion in 1 h. In the same time, the reactions with 0.002 mmol of compound A and without catalyst show approximately 28% and 3% H\/D exchange, respectively. Without the catalysts, the H\/D exchange was only 12.0% in 5 h. For compound B, 55% H\/D conversion was observed in 1 h, only when 0.05 mmol was used, which is much higher catalyst concentration. After the isolation of the chloroform fraction and two more addition of D\n                    <jats:sub>2<\/jats:sub>\n                    O, it was possible to obtain 95.0% H\/D exchange in approximately 3 h, using 0.01 mmol of the compound A. Therefore, compound A is an efficient catalyst for a rapid and straightforward synthesis of CDCl\n                    <jats:sub>3<\/jats:sub>\n                    from CHCl\n                    <jats:sub>3<\/jats:sub>\n                    at room temperature and using D\n                    <jats:sub>2<\/jats:sub>\n                    O as deuterium source.\n                  <\/jats:p>","DOI":"10.1002\/mrc.5066","type":"journal-article","created":{"date-parts":[[2020,6,20]],"date-time":"2020-06-20T08:58:18Z","timestamp":1592643498000},"page":"917-920","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A straightforward catalytic approach to obtain deuterated chloroform at room temperature"],"prefix":"10.1002","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4098-1291","authenticated-orcid":false,"given":"Angel Ruben","family":"Higuera\u2010Padilla","sequence":"first","affiliation":[{"name":"Embrapa Instrumentation  S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8530-6882","authenticated-orcid":false,"given":"Fl\u00e1vio Vin\u00edcius Criz\u00f3stomo","family":"Kock","sequence":"additional","affiliation":[{"name":"S\u00e3o Carlos Institute of Chemistry  S\u00e3o Carlos Brazil"},{"name":"Federal University of S\u00e3o Carlos  S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-2754","authenticated-orcid":false,"given":"Alzir Azevedo","family":"Batista","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos  S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9516-9022","authenticated-orcid":false,"given":"Luiz Alberto","family":"Colnago","sequence":"additional","affiliation":[{"name":"Embrapa Instrumentation  S\u00e3o Carlos 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