{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T17:22:20Z","timestamp":1782580940568,"version":"3.54.5"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T00:00:00Z","timestamp":1768694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004836","name":"Danmarks Frie Forskningsfond","doi-asserted-by":"publisher","award":["2035\u201000294B"],"award-info":[{"award-number":["2035\u201000294B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["MetaboHUB ANR\u201011\u2010INBS\u20100010"],"award-info":[{"award-number":["MetaboHUB ANR\u201011\u2010INBS\u20100010"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["MetEx+ ANR\u201021\u2010ESRE\u20100035"],"award-info":[{"award-number":["MetEx+ ANR\u201021\u2010ESRE\u20100035"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"Agence Nationale de la Recherche","doi-asserted-by":"publisher","award":["MetaboHUB (JVCE) ANR\u201024\u2010INBS\u20100012"],"award-info":[{"award-number":["MetaboHUB (JVCE) ANR\u201024\u2010INBS\u20100012"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["analyticalsciencejournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Reson in Chemistry"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Nuclear magnetic resonance (NMR) is a powerful analytical tool for wine analysis to identify and quantify a metabolite composition. However, a limiting factor of 1D\n                    <jats:sup>1<\/jats:sup>\n                    H NMR spectroscopy is the overlap of signals in complex mixtures. While conventional 2D NMR methods disperse the signals over two dimensions, they are associated with long experiment times. In the case of wine, interesting metabolites are also often masked by the large water and ethanol peaks. To improve wine analysis by NMR, a method that uses the advantages of 2D NMR while suppressing solvent signals and being within the timeframe of 1D NMR is highly desirable. Interleaved ultrafast COSY (iuf\u2010COSY) offers a possibility for fast acquisition of a 2D spectrum and has been demonstrated as a powerful tool in metabolomics studies, as a complement to 1D NMR methods. Here, the iuf\u2010COSY experiment has been adapted to suppress water and ethanol signals by using a shaped pulse and a NOESY block. This approach efficiently suppresses solvent signals and gives a 2D COSY spectrum of wine in approximately 20\u2009min. Important metabolites that originally were covered by solvent signals could be annotated, while minimal interleaving artefacts were observed. This is an efficient method to acquire a COSY spectrum of a wine sample, which can aid with the identification and discrimination of metabolites in future wine studies through additional cross peaks, while working within a high\u2010throughput time scale. This might be particularly interesting in the field of wine metabolomics, quality control, authenticity and fraud.\n                  <\/jats:p>","DOI":"10.1002\/mrc.70078","type":"journal-article","created":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T00:25:09Z","timestamp":1768782309000},"page":"416-426","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Multi\u2010Solvent Suppression Ultrafast 2D COSY for High\u2010Throughput Wine Screening"],"prefix":"10.1002","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0697-0836","authenticated-orcid":false,"given":"Pia\u00a0S.","family":"Mayer","sequence":"first","affiliation":[{"name":"Department of Food Science University of Copenhagen  Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e9r\u00e9my","family":"Marchand","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CNRS CEISAM, UMR 6230  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marine\u00a0P.\u00a0M.","family":"Letertre","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CNRS CEISAM, UMR 6230  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Nicolas","family":"Dumez","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CNRS CEISAM, UMR 6230  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4124-4338","authenticated-orcid":false,"given":"S\u00f8ren\u00a0B.","family":"Engelsen","sequence":"additional","affiliation":[{"name":"Department of Food Science University of Copenhagen  Frederiksberg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9346-9147","authenticated-orcid":false,"given":"Patrick","family":"Giraudeau","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CNRS CEISAM, UMR 6230  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,18]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"European\u2010Commission \u201cMonthly Reports on EU Agri\u2010Food Fraud Suspicions \u201d accessed October 1 2025 https:\/\/food.ec.europa.eu\/food\u2010safety\/acn\/ffn\u2010monthly_en."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf400800d"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2019.125257"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo12070672"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf204361d"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.882487"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/BK9781839168062-00377"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac500966e"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216\u2010018\u20100961\u20106"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10050203"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnmrs.2022.01.002"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.252644399"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrc.4237"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/C1AN15278E"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/ac3033504"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11306\u2010015\u20100780\u20100"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11306\u2010018\u20101360\u2010x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1039\/D4AY01225A"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.20870\/oeno\u2010one.2023.57.1.7134"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrc.2823"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23010160"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0142840"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11306\u2010015\u20100794\u20107"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmr.a.20223"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12161\u2010018\u20101310\u20102"},{"key":"e_1_2_9_27_1","unstructured":"CEISAM 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