{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T15:30:07Z","timestamp":1772811007268,"version":"3.50.1"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2007,1,11]],"date-time":"2007-01-11T00:00:00Z","timestamp":1168473600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Reproduction Devel"],"published-print":{"date-parts":[[2007,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Because estrogen may be involved in maternal recognition of pregnancy and embryonic migration in llamas, expression of estrogen receptor subtypes \u03b1 (ER\u03b1) and \u03b2 (ER\u03b2) was evaluated in corpus luteum (CL), endometrium, and uterus using relative RT\u2010PCR. Tissues were recovered from sterile\u2010mated (SM) and pregnant (PG) females during Days 7\u201311 and 7\u201313 (Day 0\u2009=\u2009day of mating), respectively, and follicular phase and juvenile females. Luteal expression of ER\u03b1 and \u03b2 was similar (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.10) in SM and PG females and within Days 7\u201311, however, expression of ER\u03b1 in ovarian tissue from follicular phase females was greater (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) than Days 7 and 9 CL. Uterus expressed less ER\u03b1 and \u03b2 compared to endometrium (<jats:italic>P<\/jats:italic>\u2009=\u20090.07 and <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01, respectively). Expression of ER\u03b1 was greater (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05) in Day 7 and follicular phase uteri than Days 9 and 11, Day 13 PG and juvenile uteri. Uterine ER\u03b2 expression was greater (<jats:italic>P<\/jats:italic>\u2009=\u20090.09) in PG versus SM females and in mated compared to follicular phase females (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). Endometrial expression of ER\u03b1 and \u03b2 did not differ (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.10) between SM and PG females or by day. The presence of luteal ER during this period may mean a role for estradiol in maternal recognition of pregnancy. Observed increases in uterine ER expression with no changes in endometrium suggest expression increased in myometrium and\/or perimetrium. Upregulation of myometrial ER\u03b2 in PG females may be involved in supporting uterine migration of the embryo. Mol. Reprod. Dev. 74: 1043\u20131052, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrd.20684","type":"journal-article","created":{"date-parts":[[2007,1,12]],"date-time":"2007-01-12T00:23:05Z","timestamp":1168561385000},"page":"1043-1052","source":"Crossref","is-referenced-by-count":13,"title":["Expression of estrogen receptors \u03b1 and \u03b2 in the corpus luteum and uterus from non\u2010pregnant and pregnant llamas"],"prefix":"10.1002","volume":"74","author":[{"given":"Susan A.","family":"Powell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bradford B.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen I.","family":"Timm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Alfred 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