{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T05:58:57Z","timestamp":1767851937673,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2008,2,20]],"date-time":"2008-02-20T00:00:00Z","timestamp":1203465600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Reproduction Devel"],"published-print":{"date-parts":[[2008,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We determined the expression of PGE2 synthase (mPGES\u20101), PGF synthase (PGFS), carbonyl reductase\/prostaglandin 9\u2010ketoreductase (CBR1) genes and the content of PGE2, PGF2\u03b1 in porcine corpora lutea on Days 12\u201314 of pregnancy and Days 12\u201314 of the estrous cycle. For this study we used a surgically\u2010generated model in which one of the uterine horns was cut transversely and a part of this horn was detached from the uterine corpus. The expression of mPGES\u20101, PGFS, and CBR1 genes and mPGES\u20101\/PGFS ratio were significantly higher in corpora lutea of the pregnant gilts compared to the corpora lutea from the parallel ovaries of the cyclic gilts. There was no difference in mPGES\u20101, PGFS, CBR1 genes expression and mPGES\u20101\/PGFS ratio between corpora lutea ipsi\u2010(CL1) and contralateral (CL2) to the uterine horn with the developing embryos. The highest content of PGE2 was found in CL1 of the pregnant gilts. The PGE2\/PGF2\u03b1 ratio was significantly higher in CL1 of the pregnant gilts compared to corpora lutea from parallel ovary of the cyclic gilts. We suggest that the activity of the investigated genes is induced by compounds of embryonic origin which are not distributed only to the ipsilateral ovary but are transported within the mesometrium to both ovaries in a more systemic manner. Mol. Reprod. Dev. 75: 1208\u20131216, 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrd.20862","type":"journal-article","created":{"date-parts":[[2008,2,20]],"date-time":"2008-02-20T17:04:00Z","timestamp":1203527040000},"page":"1208-1216","source":"Crossref","is-referenced-by-count":17,"title":["The influence of embryo presence on prostaglandins synthesis and prostaglandin E2 and F2\u03b1 content in corpora lutea during periimplantation period in the 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