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Activity localization of individual glomerulae (\u223c0.002 \u03bcL) has important consequences for understanding mechanisms in olfactory information encoding. High\u2010resolution functional MRI (fMRI) data from the rat olfactory bulb are presented using the blood oxygenation level dependent (BOLD) method at 7 T. Either individual or clusters of fMRI voxels suggestive of activity in the olfactory nerve and glomerular layers were reproducibly detected with repeated 2\u2010min exposures of iso\u2010amyl acetate at spatial resolution of 0.001\u20130.003 \u03bcL. The importance of glomerular clustering for olfaction and the implications of BOLD mapping with even higher spatial resolution (i.e., \u226a0.001 \u03bcL voxels) are discussed. High\u2010resolution in vivo mapping of the rat olfactory bulb with fMRI at high magnetic field promises to provide novel data for understanding olfaction. 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