{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T06:26:32Z","timestamp":1776752792871,"version":"3.51.2"},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2003,12,29]],"date-time":"2003-12-29T00:00:00Z","timestamp":1072656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Perfusion of left ventricular (LV) subendocardium in valvular aortic stenosis (AS) patients is impaired. It was expected that this may lead to a reduction of subendocardial fiber contraction and, consequently, to an increase of LV torsion per amount of ejection. Using MR tagging (MRT), it was investigated whether the torsion\u2010to\u2010shortening ratio (TSR) is elevated in valvular AS patients. Six asymptomatic children with valvular AS were investigated using echo Doppler, ECG, exercise test, and MRT. LV torsion and natural strain of the inner diameter were determined from measured tag displacements in two short\u2010axis slices of the LV. In all AS patients TSR was \u223c40% increased (0.62 \u00b1 0.04 rad; mean \u00b1 SD) as compared to pediatric (0.44 \u00b1 0.08 rad; n = 5) and adult controls (0.46 \u00b1 0.08 rad; n = 9), indicating subendocardial contractile dysfunction. With other techniques hitherto used this type of dysfunction could not be detected. Magn Reson Med 51:135\u2013139, 2004. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.10679","type":"journal-article","created":{"date-parts":[[2003,12,30]],"date-time":"2003-12-30T10:00:29Z","timestamp":1072778429000},"page":"135-139","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Increase in left ventricular torsion\u2010to\u2010shortening ratio in children with valvular aortic stenosis"],"prefix":"10.1002","volume":"51","author":[{"given":"Tammo","family":"Delhaas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiska","family":"Kotte","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annet","family":"van der Toorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabri\u00ebl","family":"Snoep","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frits W.","family":"Prinzen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theo","family":"Arts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,12,29]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1983.63.1.1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0033-0620(87)90016-8"},{"key":"e_1_2_6_4_2","first-page":"31","article-title":"Myocardial injury in patients with aortic stenosis","volume":"1","author":"Hutchins GM","year":"1987","journal-title":"Am J Cardiovasc Pathol"},{"key":"e_1_2_6_5_2","first-page":"116","article-title":"Second natural history study of congenital heart defects. 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