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It is shown here that this is not the case in the occipital lobe, but that this effect is often obscured at lower resolution and concealed in standard <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>\u2010weighted images. Using a high\u2010resolution (1 \u00d7 1.3 \u00d7 2 mm<jats:sup>3<\/jats:sup>) segmented EPI Carr\u2010Purcell\u2010Meiboom\u2010Gill sequence, <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> relaxation times of the brain were measured at 1.5 T for eight healthy adult volunteers. The average <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> values of cortical gray and white matter were found to be 88\u00b1 2 and 84\u00b1 3 msec in the frontal lobe, 84\u00b1 2 and 83\u00b1 3 msec in the parietal lobe, and 79\u00b1 1 and 87 \u00b1 3 msec in the occipital lobe, respectively. This unexpected occipital <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> contrast between gray and white matter is attributed to regional differences in iron concentration. Magn Reson Med 46:401\u2013406, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.1204","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T21:50:36Z","timestamp":1030312236000},"page":"401-406","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Inverse <i>T<\/i><sub>2<\/sub> contrast at 1.5 Tesla between gray matter and white matter in the occipital lobe of normal adult human brain"],"prefix":"10.1002","volume":"46","author":[{"given":"Jinyuan","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Golay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.M.","family":"van Zijl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. 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