{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:12:26Z","timestamp":1767676346439},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,11,18]],"date-time":"2005-11-18T00:00:00Z","timestamp":1132272000000},"content-version":"vor","delay-in-days":5527,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[1990,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Broadband proton\u2010decoupled natural abundance <jats:sup>13<\/jats:sup>C spectra of the human calf. liver, and head were obtained from normal volunteers and a patient with glycogen type IIIA storage disease. Two concentric and coplanar surface coils of diameters 8.0 cm and 13.0 cm were used for <jats:sup>13<\/jats:sup>C (at 16.0 MHz) and 'H (at 63.6 MHz), respectively. A WALTZ\u20108 sequence lead to homogeneous decoupling over a large volume. In addition to lipid resonances a variety of other metabolite resonances could be resolved. The glycogen concentration in the muscle and the liver of normal volunteers varied considerably depending on dietary preparation and physical exercise. The glycogen level in the liver and the calf of a patient with glycogen type IIIA storage disease was increased by a factor of 2\u20133 compared to normal. well\u2010trained volunteers. Proton\u2010decoupled <jats:sup>13<\/jats:sup>C spectra of human head are reported for the first time. The spectra are dominated by lipid resonances but an additional resonance at 54.0 ppm is clearly visible. The proton\u2010decoupled <jats:sup>13<\/jats:sup>C head spectrum of a patient with glycogen type IIIA storage disease revealed additional resonances between 71.0 and 85.0 ppm. \u00a9 1990 Academic Press, Inc.<\/jats:p>","DOI":"10.1002\/mrm.1910160114","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T12:11:31Z","timestamp":1173096691000},"page":"150-160","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Analysis of glycogen storage disease by <i>in vivo<\/i><sup>13<\/sup>C NMR comparison of normal volunteers with a patient"],"prefix":"10.1002","volume":"16","author":[{"given":"N.","family":"Beckmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Seelig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Wick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,18]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910050410"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.5.1634"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940020309"},{"key":"e_1_2_1_5_2","unstructured":"M.Saner G.McKinnon andP.Boesiger in\u201cBook of Abstracts of the Society of Magnetic Resonance in Medicine \u201d p.300 1988."},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.5.1439"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00274a015"},{"key":"e_1_2_1_8_2","first-page":"149","volume-title":"The Metabolic Basis of Inherited Disease","author":"Howell R. 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