{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T10:18:16Z","timestamp":1770718696414,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,11,18]],"date-time":"2005-11-18T00:00:00Z","timestamp":1132272000000},"content-version":"vor","delay-in-days":3884,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[1995,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Retinal hypoxia is hypothesized to initiate angiogenesis, a leading cause of blindness in developed countries. Attempts to test this hypothesis suffer from the need to use highly invasive oxygen electrodes. In this communication, noninvasive and quantitative mapping of ocular oxygenation using magnetic resonance imaging is demonstrated for the first time.<\/jats:p>","DOI":"10.1002\/mrm.1910330419","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T18:29:43Z","timestamp":1173119383000},"page":"579-581","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Quantitative Mapping of Ocular Oxygenation Using Magnetic Resonance Imaging"],"prefix":"10.1002","volume":"33","author":[{"given":"Bruce A.","family":"Berkowitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles A.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,18]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"249","article-title":"Ocular angiogenesis","volume":"28","author":"Garner A.","year":"1986","journal-title":"Int. Rev. Exp. Pathol."},{"key":"e_1_2_1_3_2","first-page":"R393","article-title":"Growth regulation of the vascular system: evidence for a metabolic hypothesis","volume":"259","author":"Adair T. H.","year":"1990","journal-title":"Am. J. Physiol."},{"key":"e_1_2_1_4_2","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1007\/BF02764304","article-title":"Oxygen and diabetic eye disease","volume":"228","author":"Stefansson E.","year":"1990","journal-title":"Graefe's Arch. Clin. Exp. Ophthalmol."},{"key":"e_1_2_1_5_2","first-page":"1933","article-title":"Comparative study of vitreous oxygen tension in human and rabbit eyes","volume":"30","author":"Sakaue H.","year":"1989","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1986.01050190121050"},{"key":"e_1_2_1_7_2","unstructured":"J. S.Hyde A.Jesmanowicz J. C.Wu Relaxation and contrast studies of the eye at high resolution in \u201cProc. SMRM 9th Annual Meeting 1990 \u201d p.667."},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.160.1.3715033"},{"issue":"13","key":"e_1_2_1_9_2","first-page":"3500","article-title":"Accurate and precise measurement of blood\u2010retinal barrier breakdown using dynamic Gd\u2010DTPA MRI","volume":"33","author":"Berkowitz B. A.","year":"1992","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1139\/v65-150"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910030214"},{"key":"e_1_2_1_12_2","first-page":"94","volume-title":"Nuclear Magnetic Resonance (NMR) Imaging","author":"Gore J. C.","year":"1983"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.143.1.7063723"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02731333"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1515\/zna-1965-1220"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmrb.1993.1075"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910310110"},{"key":"e_1_2_1_18_2","first-page":"612","article-title":"Effects of hyperoxia on the oxygen distribution in the intact cat retina","volume":"30","author":"Linsenmeier R. A.","year":"1989","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4835(90)90213-E"},{"key":"e_1_2_1_20_2","first-page":"2382","article-title":"Oxygen kinetics in the vitreous substitute perfluorotributylamine: a 19F NMR study in vivo","volume":"32","author":"Berkowitz B. A.","year":"1991","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4835(81)80016-4"},{"key":"e_1_2_1_22_2","first-page":"65","article-title":"Magnetic resonance contrast media: principles and progress","volume":"6","author":"Lauffer R. B.","year":"1990","journal-title":"Magn. Reson. Q."},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940070103"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940070104"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910060205"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006324-199112000-00013"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.1910330419","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.1910330419","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T17:39:14Z","timestamp":1698255554000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.1910330419"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4]]},"references-count":25,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,4]]}},"alternative-id":["10.1002\/mrm.1910330419"],"URL":"https:\/\/doi.org\/10.1002\/mrm.1910330419","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,4]]},"assertion":[{"value":"1994-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1994-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-11-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}