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Therefore, studies were performed applying three\u2010dimensional spatial EPR imaging at L\u2010band to image the distribution of free radical labels in the isolated heart and in phantoms of similar size. With nitroxide labels the obtainable resolution is limited by the presence of hyperfine structure in the EPR absorption function that in turn limits the maximum applicable gradient. The authors observed that with the nitroxide labels, resolutions in the range of 1\u20132 mm are possible, while with a single line glucose char label, resolutions of 0.2 mm are obtained. With the nitroxides, images were of sufficient resolution to resolve the overall global shape of the heart and the location of the left and right ventricular cavities; however, finer structures could not be resolved. With the glucose char much finer resolution could be obtained enabling visualization of the ventricles, aortic root, and proximal coronary arteries.<\/jats:p>","DOI":"10.1002\/mrm.1910340115","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T18:21:11Z","timestamp":1173118871000},"page":"99-105","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":69,"title":["Three\u2010dimensional spatial EPR imaging of the rat heart"],"prefix":"10.1002","volume":"34","author":[{"given":"Periannan","family":"Kuppusamy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penghai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay L.","family":"Zweier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,11,18]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"275","article-title":"ESR Imaging","volume":"11","author":"Ohno K.","year":"1987","journal-title":"Magn. 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