{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T20:54:10Z","timestamp":1786913650987,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,11,21]],"date-time":"2005-11-21T00:00:00Z","timestamp":1132531200000},"content-version":"vor","delay-in-days":3704,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[1995,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Five patients, each with a brain abscess, were examined by means of <jats:sup>1<\/jats:sup>H MR spectroscopic imaging <jats:italic>in vivo.<\/jats:italic> The aspirated pus was analyzed <jats:italic>in vitro<\/jats:italic> by means of 1D and 2D COSY <jats:sup>1<\/jats:sup>H MRS. In addition to resonance lines from compounds (lactate, alanine and lipids) often found in the spectra from intracranial tumors, resonance lines were detected from a number of markers of infectious involvement (acetate, succinate, and various amino acids). These results suggest that <jats:sup>1<\/jats:sup>H MRS <jats:italic>in vivo<\/jats:italic> might contribute in establishing <jats:italic>noninvasively<\/jats:italic> a differential diagnosis between brain abscess and tumor.<\/jats:p>","DOI":"10.1002\/mrm.1910340404","type":"journal-article","created":{"date-parts":[[2007,3,5]],"date-time":"2007-03-05T19:21:22Z","timestamp":1173122482000},"page":"508-514","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":86,"title":["<sup>1<\/sup>H mrs of human brain abscesses <i>in vivo<\/i> and <i>in vitro<\/i>"],"prefix":"10.1002","volume":"34","author":[{"given":"Chantal","family":"R\u00e9my","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Grand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernest Sam","family":"La\u00ef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9Rie","family":"Belle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominique","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7Ois","family":"Berger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7Ois","family":"Est\u00e8ve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Ziegler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Frsan\u00e7Ois Le","family":"Bas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alim L.","family":"Benabid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"D\u00e9corps","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph M.","family":"Segebarth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,21]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"634","article-title":"Brain abscess mimicking brain tumor","volume":"18","author":"Lau D. W.","year":"1989","journal-title":"Heart Lung"},{"key":"e_1_2_1_3_2","first-page":"1335","article-title":"Case records of the Massachusetts General Hospital, Weekly Clinicopathological Exercises, Case 43\u20141993","volume":"329","author":"Scully R. E.","year":"1994","journal-title":"N. Engl. J. Med."},{"key":"e_1_2_1_4_2","first-page":"279","article-title":"MR imaging of brain abscesses","volume":"10","author":"Haimes A. B.","year":"1989","journal-title":"Am. J. Neuroradiol."},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940050518"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.186.3.8430183"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90552-5"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(94)90092-6"},{"key":"e_1_2_1_9_2","first-page":"333","volume-title":"Physiological NMR Spectroscopy: From Isolated Cells to Man","author":"Bottomley P.","year":"1987"},{"key":"e_1_2_1_10_2","volume-title":"Principles of Nuclear Magnetic Resonance in One and Two Dimensions","author":"Ernst R. R.","year":"1987"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2364(80)90077-3"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1063\/1.432450"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2364(85)90182-9"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.16.4945"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(85)81235-7"},{"key":"e_1_2_1_16_2","first-page":"23","article-title":"Proton nuclear magnetic resonance spectra of excised rat brain. Assignment of resonances","volume":"17","author":"Ar\u00fas C.","year":"1985","journal-title":"Physiol. Chem. Phys. Med. NMR"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4165(86)90150-9"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910170202"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1994.62010166.x"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi00359a038"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910110303"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910150116"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910190119"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940070308"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940070404"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.183.3.1584924"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910130108"},{"key":"e_1_2_1_28_2","volume-title":"Anaerobe Laboratory Manual","author":"Holdeman L. V.","year":"1977"},{"key":"e_1_2_1_29_2","doi-asserted-by":"publisher","DOI":"10.1099\/00222615-11-2-81"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.29.5.428"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI108300"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.1910340404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.1910340404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T22:30:15Z","timestamp":1698273015000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.1910340404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,10]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,10]]}},"alternative-id":["10.1002\/mrm.1910340404"],"URL":"https:\/\/doi.org\/10.1002\/mrm.1910340404","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,10]]},"assertion":[{"value":"1994-12-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1995-06-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-11-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}