{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:47:34Z","timestamp":1791301654933,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,12,12]],"date-time":"2005-12-12T00:00:00Z","timestamp":1134345600000},"content-version":"vor","delay-in-days":3359,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[1996,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The authors report NMR measurements of the changes in water diffusion brought about by\n                    <jats:italic>in vivo<\/jats:italic>\n                    Wallerian degeneration due to either crush\u2010 or tie\u2010injuries in the sciatic nerve of the frog. Using a pulsed\u2010gradient spin\u2010echo sequence with a diffusion measurement time of 28 ms, the degree of diffusion coefficient anisotropy {D(longitudinal)\/D(transverse)} 4 weeks after injury in both crush\u2010 and tie\u2010injured nerves (2.3 \u00b1 0.4 and 1.7 \u00b1 0.1, respectively) is significantly less than in normal frog sciatic nerve (3.9 \u00b1 0.4). The decrease of anisotropy in the degenerated nerves is due to both a decrease in longitudinal diffusion and an increase in transverse diffusion. The changes in diffusion coefficients are compared with the degree of axonal and myelin breakdown observed in light and electron micrographs of the nerves.\n                  <\/jats:p>","DOI":"10.1002\/mrm.1910360419","type":"journal-article","created":{"date-parts":[[2007,3,12]],"date-time":"2007-03-12T02:03:50Z","timestamp":1173665030000},"page":"627-631","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":228,"title":["Changes in water diffusion due to Wallerian degeneration in peripheral nerve"],"prefix":"10.1002","volume":"36","author":[{"given":"Christian","family":"Beaulieu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Does","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard E.","family":"Snyder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter S.","family":"Allen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,12,12]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/028418518702800324"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.176.2.2367658"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217776"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217777"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199011000-00001"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199111000-00003"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.180.1.2052700"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910320506"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910360108"},{"key":"e_1_2_1_11_2","unstructured":"F.Segawa M.Kinoshita J.Kishibayashi K.Kamada N.Sunohara K.Shimizu Y.Hashimoto Diffusion images of Wallerian degeneration in\u201cProc. SMRM 12th Annual Meeting New York 1993 \u201d p.595."},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910310504"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910310408"},{"key":"e_1_2_1_14_2","first-page":"337","volume-title":"Peripheral Neuropathy","author":"Schroder J. 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Pathol."},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmrb.1994.1038"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(94)80775-1"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)91491-X"},{"key":"e_1_2_1_25_2","first-page":"296","volume-title":"Peripheral Neuropathy, Vol. 1","author":"Dyck P. 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