{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,29]],"date-time":"2023-10-29T04:40:38Z","timestamp":1698554438785},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,12,13]],"date-time":"2005-12-13T00:00:00Z","timestamp":1134432000000},"content-version":"vor","delay-in-days":2872,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[1998,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Single voxel proton spectroscopy was used to study brain metabolism in idiopathic spasmodic torticollis. Peak metabolite ratios in long echo time (135 ms) spectra were evaluated in the basal ganglia of 16 patients (29\u201065 years). Eight of them were untreated; the other eight were examined 4\u20106 weeks after administration of botulinum toxin type A. As compared with 60 control spectra, patients showed a significant, therapy\u2010resistant decrease in <jats:italic>N<\/jats:italic>\u2010acetyl\u2010L\u2010aspartate (NAA)\/choline (Cho). NAA\/cre\u2010atine (Cr) and Cho\/Cr were close to normal in the post\u2010treatment group but significantly reduced in untreated patients. This result is consistent with the hypothesis that striatal Cr is reversibly elevated in chronic muscle stimulation. The right and left stria\u2010tum were affected to the same extent.<\/jats:p>","DOI":"10.1002\/mrm.1910390219","type":"journal-article","created":{"date-parts":[[2007,3,13]],"date-time":"2007-03-13T15:51:10Z","timestamp":1173801070000},"page":"309-312","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Localized proton NMR spectroscopy in the striatum of patients with idiopathic spasmodic torticollis"],"prefix":"10.1002","volume":"39","author":[{"given":"Harald E.","family":"M\u00f6ller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliane","family":"Vollmer\u2010Haase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Wiedermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Schuierer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,12,13]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"337","volume-title":"Parkinson's Disease and Movement Disorders","author":"Jankovic J.","year":"1993"},{"key":"e_1_2_1_3_2","first-page":"585","volume-title":"Movement Disorders in Neurology and Neuropsychiatry","author":"Tarlov E.","year":"1992"},{"key":"e_1_2_1_4_2","first-page":"779","volume-title":"Neurological Disorders Course and Treatment","author":"M\u00fcller F.","year":"1996"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.40.9.1332"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.11_Part_2.79"},{"key":"e_1_2_1_7_2","first-page":"387","article-title":"Study of movement disorders and brain iron by MR","volume":"8","author":"Rutledge J. N.","year":"1987","journal-title":"Am. J. Neuroradiol."},{"key":"e_1_2_1_8_2","first-page":"223","article-title":"PET scanning in dystonia","volume":"50","author":"Martin W. R. W.","year":"1988","journal-title":"Adv. Neural."},{"key":"e_1_2_1_9_2","first-page":"1921","article-title":"Dopamine D2 receptor imaging with iodine\u2010123\u2010iodobenzamide SPECT in idiopathic rotational torticollis","volume":"35","author":"Hierholzer J.","year":"1994","journal-title":"J. Nucl Med."},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.43.12.2689"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1994.tb02749.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910330502"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410370211"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.58.6.688"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2364(86)90228-3"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900580307"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-193312000-00005"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193719330-00007"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.36.5.653"},{"key":"e_1_2_1_20_2","first-page":"243","article-title":"Brain dopaminergic system studies in patients with dystonia using positron emission tomography","volume":"50","author":"Leenders K. L.","year":"1988","journal-title":"Adv. Neurol."}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.1910390219","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.1910390219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T17:24:17Z","timestamp":1698513857000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.1910390219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,2]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,2]]}},"alternative-id":["10.1002\/mrm.1910390219"],"URL":"https:\/\/doi.org\/10.1002\/mrm.1910390219","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,2]]},"assertion":[{"value":"1997-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1997-07-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-12-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}