{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:10:59Z","timestamp":1762251059945},"reference-count":19,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,20]],"date-time":"2005-06-20T00:00:00Z","timestamp":1119225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The feasibility of performing quantitative <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> MRI in human brain at 4 T is shown. <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> values obtained from five volunteers were compared with <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> and adiabatic Carr\u2013Purcell (CP) <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> values. Measured relaxation time constants increased in order from <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>, CP\u2010<jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>, <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> both in white and gray matter, demonstrating differential sensitivities of these methods to dipolar interactions and\/or proton exchange and diffusion in local microscopic field gradients, which are so\u2010called dynamic averaging (DA) processes. In occipital lobe, all relaxation time constants were found to be higher in white matter than in gray matter, demonstrating contrast denoted as an \u201cinverse transverse relaxation contrast.\u201d This contrast persisted despite changing the delay between refocusing pulses or changing the magnitude of the spin\u2010lock field strength, which suggests that it does not originate from DA, as might be induced by the presence of Fe, but rather is related to dipolar interactions in the brain tissue. Magn Reson Med 54:14\u201319, 2005. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.20536","type":"journal-article","created":{"date-parts":[[2005,6,20]],"date-time":"2005-06-20T20:23:15Z","timestamp":1119298995000},"page":"14-19","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Quantitative <i>T<\/i><sub>1\u03c1<\/sub> and adiabatic Carr\u2013Purcell <i>T<\/i><sub>2<\/sub> magnetic resonance imaging of human occipital lobe at 4 T"],"prefix":"10.1002","volume":"54","author":[{"given":"Heidi I.","family":"Gr\u00f6hn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shalom","family":"Michaeli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Garwood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Risto A.","family":"Kauppinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olli H. 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