{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:50:07Z","timestamp":1760982607028},"reference-count":16,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,4,21]],"date-time":"2008-04-21T00:00:00Z","timestamp":1208736000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study investigated the use of peritoneal dialysis fluid (dialyzate) as a MR contrast agent to visualize the liver structure and peritoneal adhesion in rats at 7 T. Intraperitoneal injection of dialyzate (\u223c0.1 ml\/g) yielded excellent and consistent intraperitoneal enhancement that delineated the liver lobular structure in all rats studied (<jats:italic>N<\/jats:italic> = 8). It also allowed the MR detection of peritoneal adhesions that were surgically induced. MR measurements of adhesion surface areas correlated well with the postmortem estimations (<jats:italic>R<\/jats:italic> = 0.99; <jats:italic>N<\/jats:italic> = 6). Dialyzate persisted in the intraperitoneal cavity for up to 2 days. <jats:italic>T<\/jats:italic><jats:sub>1<\/jats:sub> and <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub> values of undiluted dialyzate were found to be 3017.5 \u00b1 35.3 ms and 108.4 \u00b1 2.0 ms, respectively. These findings demonstrated dialyzate\u2010enhanced MRI as a potentially valuable technique to localize certain activities within liver (such as local tumor metastasis), and to monitor therapeutic interventions (e.g., against peritoneal adhesion) in preclinical research using small animal models. Magn Reson Med 59:1170\u20131174, 2008. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.21506","type":"journal-article","created":{"date-parts":[[2008,4,21]],"date-time":"2008-04-21T22:17:27Z","timestamp":1208816247000},"page":"1170-1174","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["MRI visualization of rodent liver structure and peritoneal adhesion with dialyzate enhancement"],"prefix":"10.1002","volume":"59","author":[{"given":"Jerry S.","family":"Cheung","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph C.K.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwan","family":"Man","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kar N.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ed X.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,4,21]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s003300050485"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10555"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-871200"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2006.02.020"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.2002.6356"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000050149"},{"issue":"3","key":"e_1_2_6_8_2","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1177\/089686080102103S15","article-title":"Peritoneal dialysis solutions","volume":"21","author":"Wang T","year":"2001","journal-title":"Perit Dial Int"},{"key":"e_1_2_6_9_2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1681\/ASN.V131197","article-title":"Magnetic resonance imaging of the peritoneal cavity among peritoneal dialysis patients, using the dialyzate as \u201ccontrast medium\u201d","volume":"13","author":"Prischl FC","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-004-0271-7"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.174.4.1740987"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002470100528"},{"key":"e_1_2_6_13_2","first-page":"17","article-title":"Measurement by magnetic resonance imaging of the peritoneal membrane in contact with dialyzate in rats","volume":"21","author":"Fischbach M","year":"2005","journal-title":"Adv Perit Dial"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s005340050101"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20718"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21029"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.12.010"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.21506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.21506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T00:35:27Z","timestamp":1697157327000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.21506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4,21]]},"references-count":16,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5]]}},"alternative-id":["10.1002\/mrm.21506"],"URL":"https:\/\/doi.org\/10.1002\/mrm.21506","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,4,21]]},"assertion":[{"value":"2007-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2007-11-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2008-04-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}