{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:17:40Z","timestamp":1740104260759,"version":"3.37.3"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2010,4,30]],"date-time":"2010-04-30T00:00:00Z","timestamp":1272585600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["R01 HL74019"],"award-info":[{"award-number":["R01 HL74019"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Myocardial oxygen extraction fraction (OEF) during hyperemia can be estimated using a double\u2010inversion\u2010recovery\u2010prepared <jats:italic>T<\/jats:italic><jats:sub>2<\/jats:sub>\u2010weighted black\u2010blood sequence. Severe irregular electrocardiogram (ECG) triggering due to elevated heart rate and\/or arrhythmias may render it difficult to adequately suppress the flowing left ventricle blood signal and thus potentially cause errors in the estimates of myocardial OEF. Thus, the goal of this study was to evaluate another black\u2010blood technique, a diffusion\u2010weighted\u2010prepared turbo spin echo sequence for its ability to determine regional myocardial OEF during hyperemia. Control dogs and dogs with acute coronary artery stenosis were imaged with both the double\u2010inversion\u2010recovery\u2010 and diffusion\u2010weighted\u2010prepared turbo spin echo sequences at rest and during either dipyridamole or dobutamine hyperemia. Validation of MRI OEF estimates was performed using blood sampling from the artery and coronary sinus in control dogs. The two methods showed comparable correlations with blood sampling results (<jats:italic>R<\/jats:italic><jats:sup>2<\/jats:sup> = 0.9). Similar OEF estimations for all dogs were observed, except for the group of dogs with severe coronary stenosis during dobutamine stress. In these dogs, the diffusion\u2010weighted method provided more physiologically reasonable OEF (hyperemic OEF = 0.75 \u00b1 0.08 versus resting OEF of 0.6) than the double\u2010inversion\u2010recovery method (hyperemic OEF = 0.56 \u00b1 0.10). Diffusion\u2010weighted preparation may be a valuable alternative for more accurate oxygenation measurements during irregular ECG\u2010triggering. Magn Reson Med, 2010. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/mrm.22427","type":"journal-article","created":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T11:15:47Z","timestamp":1272712547000},"page":"1675-1682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Improvement of hyperemic myocardial oxygen extraction fraction estimation by a diffusion\u2010prepared sequence"],"prefix":"10.1002","volume":"63","author":[{"given":"Kyle S.","family":"McCommis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Koktzoglou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haosen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Goldstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin E.","family":"Northrup","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert J.","family":"Gropler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,4,30]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1940070114"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20025"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20111"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20964"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2007.04.009"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.199.1.8633172"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-004-2425-y"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20269"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20849"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21568"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(89)90005-7"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1067\/mnc.2001.120635"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.199.1.8633172"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21208"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/10976640701545206"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm0298-159"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004647-199912000-00001"},{"key":"e_1_2_5_19_2","first-page":"1950","article-title":"Effect of carbon\u201011\u2010acetate recirculation on estimates of myocardial oxygen consumption by PET","volume":"32","author":"Buck A","year":"1991","journal-title":"J Nucl Med"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20950"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21559"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1118\/1.1473135"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910380524"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.22427","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.22427","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.22427","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T12:45:14Z","timestamp":1696769114000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.22427"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,4,30]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["10.1002\/mrm.22427"],"URL":"https:\/\/doi.org\/10.1002\/mrm.22427","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"type":"print","value":"0740-3194"},{"type":"electronic","value":"1522-2594"}],"subject":[],"published":{"date-parts":[[2010,4,30]]},"assertion":[{"value":"2009-03-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-02-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2010-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}