{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:03:49Z","timestamp":1762506229670},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T00:00:00Z","timestamp":1387411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Improved diagnostic sensitivity could be obtained in cancer detection and staging when individual compounds of the choline pool can be detected. Therefore, a novel coil design is proposed, providing the ability to acquire both <jats:sup>1<\/jats:sup>H and <jats:sup>31<\/jats:sup>P magnetic resonance spectroscopic imaging (MRSI) in patients with prostate cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A two\u2010element <jats:sup>1<\/jats:sup>H\/<jats:sup>31<\/jats:sup>P endorectal coil was designed by adjusting a commercially available 3T endorectal coil. The two\u2010element coil setup was interfaced as a transceiver to a whole body 7T MR scanner. Simulations and phantom measurements were performed to compare the efficiency of the coil. <jats:sup>1<\/jats:sup>H MRSI and <jats:sup>31<\/jats:sup>P MRSI were acquired in vivo in prostate cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The efficiency of the <jats:sup>1<\/jats:sup>H\/<jats:sup>31<\/jats:sup>P coil is comparable to the dual channel <jats:sup>1<\/jats:sup>H coil previously published. Individually distinguishable phospholipid metabolites in the in vivo <jats:sup>31<\/jats:sup>P spectra were: phosphoethanolamine, phosphocholine, phosphate, glycerophosphoethanolamine, glycerophosphocholine, phosphocreatine, and adenosine triposphate. <jats:sup>1<\/jats:sup>H MRSI was performed within the same scan session, visualizing choline, polyamines, creatine, and citrate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:sup>1<\/jats:sup>H MRSI and <jats:sup>31<\/jats:sup>P MRSI can be acquired in the human prostate at 7T within the same scan session using an endorectal coil matched and tuned for <jats:sup>1<\/jats:sup>H (quadrature) and <jats:sup>31<\/jats:sup>P (linear) without the need of cable traps and with negligible efficiency losses in the <jats:sup>1<\/jats:sup>H and <jats:sup>31<\/jats:sup>P channel. Magn Reson Med 72:1516\u20131521, 2014. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.25070","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T18:27:49Z","timestamp":1387477669000},"page":"1516-1521","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["<sup>31<\/sup>P MR spectroscopic imaging combined with <sup>1<\/sup>H MR spectroscopic imaging in the human prostate using a double tuned endorectal coil at 7T"],"prefix":"10.1002","volume":"72","author":[{"given":"Mariska P.","family":"Luttje","sequence":"first","affiliation":[{"name":"Imaging Division University Medical Center Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michel G. 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M.","family":"van der Kemp","sequence":"additional","affiliation":[{"name":"Imaging Division University Medical Center Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter R.","family":"Luijten","sequence":"additional","affiliation":[{"name":"Imaging Division University Medical Center Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"van Vulpen","sequence":"additional","affiliation":[{"name":"Imaging Division University Medical Center Utrecht Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uulke A.","family":"van der Heide","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy the Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital Amsterdam Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis W. 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