{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T13:45:36Z","timestamp":1767015936602},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T00:00:00Z","timestamp":1394668800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2015,2]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Conventional calculation of myocardial strain requires tissue\u2010tracking. A surrogate for strain called global fractional shortening (GFS) is proposed based on changes in dimensions of endocardial and epicardial surfaces without tissue\u2010tracking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three\u2010dimensional endocardial and epicardial left ventricular surfaces traced at end\u2010diastole and end\u2010systole using conventional steady\u2010state free precession cine images were used to calculate <jats:italic>GFS<jats:sub>cc<\/jats:sub><\/jats:italic> (circumferential), <jats:italic>GFS<jats:sub>ll<\/jats:sub><\/jats:italic> (longitudinal), and <jats:italic>GFS<jats:sub>rr<\/jats:sub><\/jats:italic> (radial) using fractional length changes in each direction over the heart surface. GFS values were validated using finite element models (FEM) and in vivo using tagging\u2010derived strains (<jats:italic>\u03b5<jats:sub>cc<\/jats:sub>,\u03b5<jats:sub>ll<\/jats:sub>,\u03b5<jats:sub>rr<\/jats:sub><\/jats:italic>) in patients with a wide range of ejection fraction (EF) and diagnosis (n\u2009=\u200932). GFS was also measured in 31 patients with Fabry disease and matched healthy controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>GFS values were within 3% of average FEM\u2010derived Lagrangian strains and had good agreement in vivo (<jats:italic>GFS<jats:sub>cc<\/jats:sub><\/jats:italic>\u2009=\u2009\u221214\u2009\u00b1\u20094%, <jats:italic>\u03b5<jats:sub>cc<\/jats:sub><\/jats:italic>\u2009=\u2009\u221214\u2009\u00b1\u20094%, R<jats:sup>2<\/jats:sup>\u2009=\u20090.85; <jats:italic>GFS<jats:sub>ll<\/jats:sub><\/jats:italic>\u2009=\u2009\u221212\u2009\u00b1\u20094%, <jats:italic>\u03b5<jats:sub>ll<\/jats:sub><\/jats:italic>\u2009=\u2009\u221212\u2009\u00b1\u20094%, R<jats:sup>2<\/jats:sup>\u2009=\u20090.72; <jats:italic>GFS<jats:sub>rr<\/jats:sub><\/jats:italic>\u2009=\u200946\u2009\u00b1\u200921%). <jats:italic>\u03b5<jats:sub>rr<\/jats:sub><\/jats:italic> could not be measured reliably from tagging. Compared with healthy controls with matched EF, patients with Fabry disease had significantly increased <jats:italic>GFS<jats:sub>cc (Endo)<\/jats:sub><\/jats:italic> (\u221228\u2009\u00b1\u20093% versus \u221225\u2009\u00b1\u20092%), decreased <jats:italic>GFS<jats:sub>cc(Epi)<\/jats:sub><\/jats:italic> (\u221210\u2009\u00b1\u20092% versus \u221211\u2009\u00b1\u20092%) and decreased <jats:italic>GFS<jats:sub>ll<\/jats:sub><\/jats:italic> for all components.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>GFS yields similar values to conventionally measured strains without requiring tissue\u2010tracking. Compared with controls, patients with Fabry disease have significant differences in several GFS components. <jats:bold>Magn Reson Med 73:586\u2013596, 2015. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.25166","type":"journal-article","created":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T15:13:42Z","timestamp":1394723622000},"page":"586-596","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Quantification of circumferential, longitudinal, and radial global fractional shortening using steady\u2010state free precession cines: A comparison with tissue\u2010tracking strain and application in fabry disease"],"prefix":"10.1002","volume":"73","author":[{"given":"June","family":"Cheng\u2010Baron","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelvin","family":"Chow","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph J.","family":"Pagano","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kumaradevan","family":"Punithakumar","sequence":"additional","affiliation":[{"name":"Servier Virtual Cardiac Centre, Mazankowski Alberta Heart Institute and Department of Radiology and Diagnostic Imaging University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. Ian","family":"Paterson","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin Y.","family":"Oudit","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard B.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering University of Alberta Edmonton Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,3,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2008.10.006"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.07.009"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.955542"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2011.08.003"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jer318"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi143"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.794529"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.063"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2009.173997"},{"key":"e_1_2_7_11_1","first-page":"356","article-title":"Prediction of all\u2010cause mortality from global longitudinal speckle strain: comparison with ejection fraction and wall motion scoring","volume":"2","author":"Stanton T","year":"2009","journal-title":"Circulation"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0894-7317(98)70151-8"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.10.040"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(199912)42:6<1048::AID-MRM9>3.0.CO;2-M"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.172.2.2748813"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910150215"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910300207"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004424-199412000-00005"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmre.1998.1676"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1195"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2009.11.006"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-13-58"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-7120-7-53"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2012.11.012"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-32"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-14-43"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.09.005"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.113.000482"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00131.2010"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0b013e318154b1dc"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1081\/JCMR-120016389"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-097X.2008.00799.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.2.r00fe17453"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880020209"},{"issue":"1","key":"e_1_2_7_35_1","first-page":"340","article-title":"A parameterization of deformation fields for diffeomorphic image registration and its application to myocardial delineation","volume":"13","author":"Chen HM","year":"2010","journal-title":"Med Image Comput Comput Assist Interv"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/10976640500295516"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(02)02381-0"},{"key":"e_1_2_7_38_1","first-page":"137","article-title":"Improved left ventricular mass quantification with partial voxel interpolation: in vivo and necropsy validation of a novel cardiac MRI segmentation algorithm","volume":"5","author":"Codella NC","year":"2010","journal-title":"Circulation"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2010.04.013"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2011.10.019"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.4960020404"},{"key":"e_1_2_7_42_1","first-page":"5","article-title":"The relative impact of circumferential and longitudinal shortening on left ventricular ejection fraction and stroke volume","volume":"17","author":"MacIver DH","year":"2012","journal-title":"Exp Clin Cardiol"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00153-Q"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00601-X"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.06.072"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20070066"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.12.047"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/10976640500295417"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.25166","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.25166","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.25166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T22:46:41Z","timestamp":1696373201000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.25166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,13]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["10.1002\/mrm.25166"],"URL":"https:\/\/doi.org\/10.1002\/mrm.25166","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,13]]},"assertion":[{"value":"2013-07-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-03-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}