{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:29:36Z","timestamp":1770834576751,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T00:00:00Z","timestamp":1432252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"NSF","award":["CBET-1265612"],"award-info":[{"award-number":["CBET-1265612"]}]},{"name":"NIH\/NIAMS","award":["P50 AR060752"],"award-info":[{"award-number":["P50 AR060752"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To accelerate <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> quantification in cartilage imaging using combined compressed sensing with iterative locally adaptive support detection and JSENSE.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>To reconstruct <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> images from accelerated acquisition at different time of spin\u2010lock (TSLs), we propose an approach to combine an advanced compressed sensing (CS) based reconstruction technique, LAISD (locally adaptive iterative support detection), and an advanced parallel imaging technique, JSENSE. Specifically, the reconstruction process alternates iteratively among local support detection in the domain of principal component analysis, compressed sensing reconstruction of the image sequence, and sensitivity estimation with JSENSE. <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> quantification results from accelerated scans using the proposed method are evaluated using in vivo knee cartilage data from bilateral scans of three healthy volunteers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> maps obtained from accelerated scans (acceleration factors of 3 and 3.5) using the proposed method showed results comparable to conventional full scans. The <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> errors in all compartments are below 1%, which is well below the in vivo reproducibility of cartilage <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> reported from previous studies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The proposed method can significantly accelerate the acquisition process of <jats:italic>T<\/jats:italic><jats:sub>1\u03c1<\/jats:sub> quantification on human cartilage imaging without sacrificing accuracy, which will greatly facilitate the clinical translation of quantitative cartilage MRI. <jats:bold>Magn Reson Med 75:1617\u20131629, 2016. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:bold><\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.25773","type":"journal-article","created":{"date-parts":[[2015,5,22]],"date-time":"2015-05-22T15:37:26Z","timestamp":1432309046000},"page":"1617-1629","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Accelerating <i>t<\/i><sub>1\u03c1<\/sub> cartilage imaging using compressed sensing with iterative locally adapted support detection and JSENSE"],"prefix":"10.1002","volume":"75","author":[{"given":"Yihang","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering Department of Electrical Engineering State University of New York at Buffalo Buffalo USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prachi","family":"Pandit","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging University of California San Francisco USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Pedoia","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging University of California San Francisco USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julien","family":"Rivoire","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging University of California San Francisco USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhua","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Department of Electrical Engineering State University of New York at Buffalo Buffalo USA"},{"name":"School of Information and Electronics, Beijing Institute of Technology Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Liang","sequence":"additional","affiliation":[{"name":"Paul C. 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