{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:05:01Z","timestamp":1791824701134,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,8,30]],"date-time":"2017-08-30T00:00:00Z","timestamp":1504051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Philips Healthcare"},{"name":"Skope Magnetic Resonance Technologies"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>MRI of tissues with short coherence lifetimes T<jats:sub>2<\/jats:sub> or \n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0003.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0003\"\/> can be performed efficiently using zero echo time (ZTE) techniques such as algebraic ZTE, pointwise encoding time reduction with radial acquisition (PETRA), and water\u2010 and fat\u2010suppressed proton projection MRI (WASPI). They share the principal challenge of recovering data in central k\u2010space missed due to an initial radiofrequency dead time. The purpose of this study was to compare the three techniques directly, with a particular focus on their behavior in the presence of ultra\u2013short\u2010lived spins.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The most direct comparison was enabled by aligning acquisition and reconstruction strategies of the three techniques. Image quality and short\u2010\n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0004.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0004\"\/> performance were investigated using point spread functions, 3D simulations, and imaging of phantom and bone samples with short (&lt;1 ms) and ultra\u2010short (&lt;100\u2009\u03bcs) \n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0005.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0005\"\/>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Algebraic ZTE offers favorable properties but is limited to k\u2010space gaps up to approximately three Nyquist dwells. At larger gaps, PETRA enables robust imaging with little compromise in image quality, whereas WASPI may be prone to artifacts from ultra\u2010short \n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0006.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0006\"\/> species.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>For small k\u2010space gaps (&lt;4 dwells) and \n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0007.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0007\"\/> much larger than the dead time, all techniques enable artifact\u2010free short\u2010\n<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mrm26875-math-0008.png\" xlink:title=\"urn:x-wiley:07403194:media:mrm26875:mrm26875-math-0008\"\/> MRI. However, if these requirements are not fulfilled careful consideration is needed and PETRA will generally achieve better image quality. Magn Reson Med 79:2036\u20132045, 2018. \u00a9 2017 International Society for Magnetic Resonance in Medicine.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.26875","type":"journal-article","created":{"date-parts":[[2017,8,31]],"date-time":"2017-08-31T08:14:35Z","timestamp":1504167275000},"page":"2036-2045","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Filling the dead\u2010time gap in zero echo time MRI: Principles compared"],"prefix":"10.1002","volume":"79","author":[{"given":"Romain","family":"Froidevaux","sequence":"first","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Weiger","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David O.","family":"Brunner","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin E.","family":"Dietrich","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertram J.","family":"Wilm","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaas P.","family":"Pruessmann","sequence":"additional","affiliation":[{"name":"Institute for Biomedical Engineering ETH Zurich and University of Zurich Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,30]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.2906"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmr.2012.12.011"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.3990"},{"key":"e_1_2_5_5_1","unstructured":"NayakKS PaulyJM GoldGE NishimuraDG.Imaging Ultra\u2010short T2 Species in the Brain. In Proceedings of the 8th Annual Meeting of ISMRM Denver Colorado USA 2000. p.509."},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21104"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.10.053"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21230"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13244-012-0176-x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.23712"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880020109"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmre.1999.1767"},{"key":"e_1_2_5_13_1","first-page":"311","article-title":"MRI with zero echo time","volume":"1","author":"Weiger M","year":"2012","journal-title":"eMagRes"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21174"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23017"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22637"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.15141655"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-014-0459-y"},{"key":"e_1_2_5_19_1","first-page":"1","article-title":"Exploring the bandwidth limits of ZTE imaging: spatial response, out\u2010of\u2010band signals, and noise propagation","author":"Weiger M","year":"2014","journal-title":"Magn Reson Med"},{"key":"e_1_2_5_20_1","unstructured":"FroidevauxR WeigerM BrunnerDO WilmBJ DietrichBE PruessmannKP.Filling the Dead Time Gap in Zero Echo Time MRI: Principles Compared. In Proceedings of the 24th Annual Meeting of ISMRM Singapore 2016. p.3298."},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1109\/42.97598"},{"key":"e_1_2_5_22_1","first-page":"665","article-title":"Rapid 3\u2010D reconstruction from 1\u2010D projections for metabolic MR imaging of short T2 species","volume":"1992","author":"Chesler D","year":"1992","journal-title":"Proc Int Soc Magn Reson Med"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(199901)41:1<179::AID-MRM25>3.0.CO;2-V"},{"key":"e_1_2_5_24_1","first-page":"638","volume":"651","author":"Pruessmann KP","year":"2001","journal-title":"Advances in sensitivity encoding with arbitrary k\u2010space trajectories"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmr.2015.12.016"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25770"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.3305"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10334-015-0509-0"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22130"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26368"},{"key":"e_1_2_5_31_1","unstructured":"WeigerM OverwegJ R\u00f6slerMB et al.An insert gradient for zero\u2010echo\u2010time imaging with 200 mT\/m at full duty cycle. In Proceedings of the 25th Annual Meeting of ISMRM Honolulu Hawaii USA 2017. p.2681."}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.26875","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.26875","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mrm.26875","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.26875","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T09:49:36Z","timestamp":1693993776000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.26875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,30]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["10.1002\/mrm.26875"],"URL":"https:\/\/doi.org\/10.1002\/mrm.26875","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,30]]},"assertion":[{"value":"2017-04-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}