{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T13:28:00Z","timestamp":1762522080087},"reference-count":46,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,10,13]],"date-time":"2017-10-13T00:00:00Z","timestamp":1507852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["MOP\u201093531"],"award-info":[{"award-number":["MOP\u201093531"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To achieve consistent effectiveness in reconstruction of fine image features for cases of varying contrast\u2010to\u2010noise ratio (CNR) to facilitate translating accelerated multicontrast volumetric imaging with isotropic resolution toward clinical utility in peri\u2010infarct characterization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Theory and Methods<\/jats:title><jats:p>A low\u2010rank and spatially varying edge\u2010preserving constrained compressed sensing parallel imaging reconstruction method (CP\u2010LASER) is developed to effectively preserve contrast of small\u2010scale structures for highly accelerated multicontrast volumetric imaging in CNR\u2010limited scenarios. CP\u2010LASER synergistically integrates parallel imaging, low\u2010rank and spatially varying edge\u2010preserving sparse modeling to achieve high signal\u2010to\u2010noise\u2010ratio efficiency by leveraging prior knowledge about signal properties including coil sensitivity weighting, spatiotemporally correlated signal relaxation, and spatially varying sparsity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the preclinical study using highly accelerated multicontrast volumetric imaging with an isotropic 1.5\u2010mm resolution, CP\u2010LASER demonstrated robust multicontrast reconstruction of peri\u2010infarct characteristics with excellent correspondence with histopathology. CP\u2010LASER provides better delineation of the peri\u2010infarct border zone with improved sharpness than alternative methods in a clinical demonstration on 1.5T with an isotropic 2.2\u2010mm resolution achieved in a single breath\u2010hold.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Accelerated multicontrast volumetric imaging with isotropic resolution using CP\u2010LASER has demonstrated the potential to improve peri\u2010infarct characterization in a clinical setting. Magn Reson Med 79:3018\u20133031, 2018. \u00a9 2017 International Society for Magnetic Resonance in Medicine.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.26970","type":"journal-article","created":{"date-parts":[[2017,10,14]],"date-time":"2017-10-14T03:58:41Z","timestamp":1507953521000},"page":"3018-3031","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Accelerated multicontrast volumetric imaging with isotropic resolution for improved peri\u2010infarct characterization using parallel imaging, low\u2010rank and spatially varying edge\u2010preserving sparse modeling"],"prefix":"10.1002","volume":"79","author":[{"given":"Li","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Medical Biophysics University of Toronto Toronto Ontario Canada"},{"name":"Schulich Heart Research Program and Physical Sciences Platform, Sunnybrook Research Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Lai","sequence":"additional","affiliation":[{"name":"Global Applied Science Laboratory GE Healthcare Menlo Park California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mihaela","family":"Pop","sequence":"additional","affiliation":[{"name":"Department of Medical Biophysics University of Toronto Toronto Ontario Canada"},{"name":"Schulich Heart Research Program and Physical Sciences Platform, Sunnybrook Research Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham A.","family":"Wright","sequence":"additional","affiliation":[{"name":"Department of Medical Biophysics University of Toronto Toronto Ontario Canada"},{"name":"Schulich Heart Research Program and Physical Sciences Platform, Sunnybrook Research Institute Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.653568"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.108.826529"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.01.007"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-15-0606"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2016.01.033"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.07.043"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.107.158980"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.108.835793"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2014.2336593"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.000264"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euu310"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.100.19.1992"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200011163432003"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21296"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21897"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11102216"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.12112489"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24969"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24494"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21391"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(199911)42:5<952::AID-MRM16>3.0.CO;2-S"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10171"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22428"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21291"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2009.2023515"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.22394"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/1532-429X-15-57"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21505"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21907"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26402"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24751"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910160203"},{"key":"e_1_2_8_34_1","unstructured":"WuB MillaneR WattsR BonesP.Applying compressed sensing in parallel MRI. In Proceedings of the 16th Annual Meeting of ISMRM Toronto Canada 2008. p. 1480."},{"key":"e_1_2_8_35_1","unstructured":"KingK.Combining compressed sensing and parallel imaging. In Proceedings of the 16th Annual Meeting of ISMRM Toronto Canada 2008. Abstract 1480."},{"key":"e_1_2_8_36_1","unstructured":"LiuB SebertF ZouY YingL.SparseSENSE: randomly\u2010sampled parallel imaging using compressed sensing. In Proceedings of the 16th Annual Meeting of ISMRM Toronto Canada 2008. Abstract 3154."},{"key":"e_1_2_8_37_1","unstructured":"AlleyMT MurphyMJ KeutzerK LustigM VasanawalaSS.Improved time\u2010resolved 3D phase contrast imaging through variable Poisson sampling and partial respiratory triggering. In Proceedings of the 19th Annual Meeting of ISMRM Montreal Canada 2011. Abstract 1218."},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/58\/15\/5009"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25161"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24267"},{"key":"e_1_2_8_41_1","unstructured":"BahriD UeckerM KeutzerK LustigM.ESPIRIT\u2010based coil compression for cartesian sampling. In Proceedings of the 21st Annual Meeting of ISMRM Salt Lake City Utah USA 2013. Abstract 2657."},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511809071"},{"key":"e_1_2_8_43_1","unstructured":"UeckerM VirtueP OngF MurphyMJ AlleyM VasanawalaS ML.Software toolbox and programming library for compressed sensing and parallel imaging. In ISMRM Scientific Workshop \u2010 Data Sampling and Image Reconstruction Sedona Arizona USA 2013. Abstract number: Section 8 Number 6."},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910380524"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1137\/S1064827598344169"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1137\/090769521"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22595"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmrm.26970","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.26970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T20:17:15Z","timestamp":1695673035000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.26970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,13]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1002\/mrm.26970"],"URL":"https:\/\/doi.org\/10.1002\/mrm.26970","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,13]]},"assertion":[{"value":"2017-04-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-09-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}