{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:20:28Z","timestamp":1789932028120,"version":"4.0.1"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,10,12]],"date-time":"2018-10-12T00:00:00Z","timestamp":1539302400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["NIH K23 HL112910"],"award-info":[{"award-number":["NIH K23 HL112910"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["NIH R01 HL131919"],"award-info":[{"award-number":["NIH R01 HL131919"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004830","name":"Siemens","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004830","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To develop and evaluate a simultaneous multislice (SMS) spiral perfusion pulse sequence with whole\u2010heart coverage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An orthogonal set of phase cycling angles following a Hadamard pattern was incorporated into a golden\u2010angle (GA) variable density spiral perfusion sequence to perform SMS imaging at different multiband (MB) factors. Images were reconstructed using an SMS extension of L1\u2010SPIRiT that we have termed SMS\u2010L1\u2010SPIRiT. The proposed sequence was evaluated in 40 subjects (10 each for MB factors of 1, 2, 3, and 4). Images were blindly graded by 2 cardiologists on a 5\u2010point scale (5, excellent). To quantitatively evaluate the reconstruction performance against images acquired without SMS, the MB =1 data were used to retrospectively simulate data acquired at MB factors of 2 to 4.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Analysis of the SMS point\u2010spread function for the desired slice showed that the proposed sampling strategy significantly canceled the main\u2010lobe energy of the other slices and has low side\u2010lobe energy resulting in an incoherent temporal aliasing pattern when rotated by the GA. Retrospective experiments demonstrated the SMS\u2010L1\u2010SPIRiT method removed aliasing from the interfering slices and showed excellent agreement with the ground\u2010truth MB =1 images. Clinical evaluation demonstrated high\u2010quality perfusion images with average image\u2010quality scores of 4.3\u00a0\u00b1\u00a00.5 (MB =2), 4.2\u00a0\u00b1\u00a00.5 (MB =3), and 4.4\u00a0\u00b1\u00a00.4 (MB =4) with no significant quality difference in image quality between MB factors (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.38).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>SMS spiral perfusion at MB factors 2, 3, and 4 produces high\u2010quality perfusion images with whole\u2010heart coverage in a clinical setting with high sampling efficiency.<\/jats:p>\n                  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