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We acquire interleaved high\u2013spatial resolution image data and high\u2013temporal resolution auxiliary data following inversion\u2010recovery pulses at set intervals and perform low\u2010rank tensor imaging to reconstruct images at 344 inversion times, 20 cardiac phases, and 6 respiratory phases. The accuracy and repeatability of Multitasking T<jats:sub>1<\/jats:sub> mapping in generating native T<jats:sub>1<\/jats:sub> and ECV maps are compared with conventional techniques in a phantom, a simulation, 12 healthy subjects, and 10 acute myocardial infarction patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In phantoms, Multitasking T<jats:sub>1<\/jats:sub> mapping correlated strongly with the gold\u2010standard spin\u2010echo inversion recovery (R<jats:sup>2<\/jats:sup> = 0.99). A simulation study demonstrated that Multitasking T<jats:sub>1<\/jats:sub> mapping has similar myocardial sharpness to the fully sampled ground truth. In vivo native T<jats:sub>1<\/jats:sub> and ECV values from Multitasking T<jats:sub>1<\/jats:sub> mapping agree well with conventional MOLLI values and show good repeatability for native T<jats:sub>1<\/jats:sub> and ECV mapping for 60 seconds, 30 seconds, or 15 seconds of data. Multitasking native T<jats:sub>1<\/jats:sub> and ECV in myocardial infarction patients correlate positively with values from MOLLI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Multitasking T<jats:sub>1<\/jats:sub> mapping can quantify native T<jats:sub>1<\/jats:sub> and ECV in the myocardium with free\u2010breathing, non\u2010ECG, continuous scans with good image quality and good repeatability in vivo in healthy subjects, and correlation with MOLLI T<jats:sub>1<\/jats:sub> and ECV in acute myocardial infarction patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.27574","type":"journal-article","created":{"date-parts":[[2018,11,19]],"date-time":"2018-11-19T09:00:53Z","timestamp":1542618053000},"page":"2450-2463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Free\u2010breathing, non\u2010ECG, continuous myocardial T<sub>1<\/sub> mapping with cardiovascular magnetic resonance multitasking"],"prefix":"10.1002","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2730-5982","authenticated-orcid":false,"given":"Jaime L.","family":"Shaw","sequence":"first","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"},{"name":"Department of Bioengineering University of California Los Angeles California"},{"name":"Smidt Heart Institute, Cedars\u2010Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Yang","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"},{"name":"Department of Radiology Xuanwu Hospital Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7469-2658","authenticated-orcid":false,"given":"Zhengwei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixin","family":"Deng","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"},{"name":"Department of Bioengineering University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debiao","family":"Li","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"},{"name":"Department of Bioengineering University of California Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9334-8684","authenticated-orcid":false,"given":"Anthony G.","family":"Christodoulou","sequence":"additional","affiliation":[{"name":"Biomedical Imaging Research Institute, Cedars\u2010Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,19]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.307974"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.113.001541"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.08.019"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.11.013"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2012-302346"},{"key":"e_1_2_7_7_1","first-page":"210","article-title":"T1 mapping in dilated cardiomyopathy with cardiac magnetic resonance: quantification of diffuse myocardial fibrosis and comparison with endomyocardial biopsy. 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