{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:43:30Z","timestamp":1790289810188,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003921","name":"Department of Health, Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To develop an accelerated motion corrected 3D whole\u2010heart imaging approach (qBOOST\u2010T2) for simultaneous high\u2010resolution bright\u2010 and black\u2010blood cardiac MR imaging and quantitative myocardial T2 characterization.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Three undersampled interleaved balanced steady\u2010state free precession cardiac MR volumes were acquired with a variable density Cartesian trajectory and different magnetization preparations: (1) T2\u2010prepared inversion recovery (T2prep\u2010IR), (2) T2\u2010preparation, and (3) no preparation. Image navigators were acquired prior the acquisition to correct for 2D translational respiratory motion. Each 3D volume was reconstructed with a low\u2010rank patch\u2010based reconstruction. The T2prep\u2010IR volume provides bright\u2010blood anatomy visualization, the black\u2010blood volume is obtained by means of phase sensitive reconstruction between first and third datasets, and T2 maps are generated by matching the signal evolution to a simulated dictionary. The proposed sequence has been evaluated in simulations, phantom experiments, 11 healthy subjects and compared with 3D bright\u2010blood cardiac MR and standard 2D breath\u2010hold balanced steady\u2010state free precession T2 mapping. The feasibility of the proposed approach was tested on 4 patients with suspected cardiovascular disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>High linear correlation (y = 1.09 \u00d7 \u22120.83, R<jats:sup>2<\/jats:sup> = 0.99) was found between the proposed qBOOST\u2010T2 and T2 spin echo measurements in phantom experiment. Good image quality was observed in vivo with the proposed 4x undersampled qBOOST\u2010T2. Mean T2 values of 53.1 \u00b1 2.1 ms and 55.8 \u00b1 2.7 ms were measured in vivo for 2D balanced steady\u2010state free precession T2 mapping and qBOOST\u2010T2, respectively, with linear correlation of y = 1.02x+1.46 (R<jats:sup>2<\/jats:sup> = 0.61) and T2 bias = 2.7 ms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The proposed qBOOST\u2010T2 sequence allows the acquisition of 3D high\u2010resolution co\u2010registered bright\u2010 and black\u2010blood volumes and T2 maps in a single scan of ~11 min, showing promising results in terms of T2 quantification.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.28039","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T07:53:05Z","timestamp":1571644385000},"page":"1673-1687","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["3D Whole\u2010heart free\u2010breathing qBOOST\u2010T2 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