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Examinations of 13 volunteers were performed on a 7T MRI system with 3 different types of pulse sequences: (1) saturation in circular polarized (CP) mode and CP mode readout, (2) MIMOSA and CP readout, and (3) MIMOSA and FOCUS readout. For comparison, the inverse magnetic transfer ratio metric for relayed nuclear Overhauser effect and amide proton transfer were calculated. To investigate the number of required acquisitions for a good correction, 4 volunteers were measured with 6 different B1<\/jats:sub> amplitudes. Finally, time point repeatability was investigated for 6 volunteers.<\/jats:p><\/jats:sec>Results<\/jats:title>MIMOSA FOCUS sequence using correction, with both single and multiple points, reduced inhomogeneity of the CEST contrasts around the occipital lobe and cerebellum. Results indicate that the most stable inter\u2010subject coefficient of variation was achieved using the MIMOSA FOCUS sequence. Time point repeatability of MIMOSA FOCUS with single\u2010point correction showed a maximum coefficient of variation below 8% for 3 measurements in a single volunteer.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>A combination of MIMOSA FOCUS with a single\u2010point correction can be used to achieve quantitative CEST measurements at ultra\u2010high magnetic field strengths. Compared to previous correction methods, acquisition time can be reduced as additional scans required for correction can be omitted.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.28745","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T08:17:08Z","timestamp":1614327428000},"page":"346-362","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Whole\u2010brain quantitative CEST MRI at 7T using parallel transmission methods and correction"],"prefix":"10.1002","volume":"86","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8450-3021","authenticated-orcid":false,"given":"Andrzej","family":"Liebert","sequence":"first","affiliation":[{"name":"Institute of Radiology University Hospital Erlangen Friedrich\u2010Alexander\u2010Universit\u00e4t Erlangen\u2010N\u00fcrnberg (FAU) Erlangen 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