{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:25:55Z","timestamp":1790745955292,"version":"4.1.0"},"reference-count":58,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T00:00:00Z","timestamp":1653350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DFG 397806429"],"award-info":[{"award-number":["DFG 397806429"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>To introduce phase\u2010cycled balanced SSFP (bSSFP) acquisition as an alternative in Fourier decomposition MRI for improved robustness against field inhomogeneities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Series 2D dynamic lung images were acquired in 5 healthy volunteers at 1.5 T and 3\u00a0T using bSSFP sequence with multiple RF phase increments and compared with conventional single RF phase increment acquisitions. The approach was evaluated based on functional map homogeneity analysis, while ensuring image and functional map quality by means of SNR and contrast\u2010to\u2010noise ratio analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At both field strengths, functional maps obtained with phase\u2010cycled acquisitions displayed improved robustness against local signal losses compared with single\u2010phase acquisitions. The coefficient of variation (mean\u00a0\u00b1\u2009SD, across volunteers) measured in the ventilation maps resulted in 29.7\u2009\u00b1\u20092.6 at 1.5\u00a0T and 37.5\u2009\u00b1\u20093.1 at 3\u00a0T for phase\u2010cycled acquisitions, compared with 39.9\u2009\u00b1\u20095.2 at 1.5\u00a0T and 49.5\u2009\u00b1\u20093.7 at 3\u00a0T for single\u2010phase acquisitions, indicating a significant improvement () in ventilation map homogeneity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Phase\u2010cycled bSSFP acquisitions improve robustness against field inhomogeneity artifacts and significantly improve ventilation map homogeneity at both field strengths. As such, phase\u2010cycled bSSFP may serve as a robust alternative in lung function assessments.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.29302","type":"journal-article","created":{"date-parts":[[2022,5,24]],"date-time":"2022-05-24T11:30:45Z","timestamp":1653391845000},"page":"1764-1774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Phase\u2010cycled balanced SSFP imaging for non\u2010contrast\u2010enhanced functional lung imaging"],"prefix":"10.1002","volume":"88","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7062-018X","authenticated-orcid":false,"given":"Efe","family":"Ilicak","sequence":"first","affiliation":[{"name":"Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim Heidelberg University Mannheim 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