{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:18:20Z","timestamp":1789625900927,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["885876"],"award-info":[{"award-number":["885876"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:sec><jats:title>Purpose<\/jats:title><jats:p>Assess short\u2010term and long\u2010term effects of chronic exposure to an ultrahigh static magnetic (B<jats:sub>0<\/jats:sub>) field on mice inner ear in the context of MR safety of human scanning at 11.7\u2009T.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Mice were chronically exposed to a B<jats:sub>0<\/jats:sub> field of 11.7 T or 17.2 T during ten 2\u2010h exposure sessions evenly distributed over a period of 5\u2009weeks, resulting in a total of 20\u2009h of exposure per mouse. During exposure sessions, mice were anesthetized and positioned either parallel or antiparallel to B<jats:sub>0<\/jats:sub>. Before, during, and 2\u2009weeks after the magnetic\u2010field exposure period, mice performed behavioral tests (balance beam, rotarod, and swim tests) to evaluate their short\u2010term and long\u2010term motor coordination and balance. An auditory brainstem response (ABR) test was finally performed to assess the functional integrity of mice cochlea, 2\u2009weeks after the last exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After awaking from anesthesia following B<jats:sub>0<\/jats:sub> exposures at 11.7 Tor 17.2 T, mice displayed a transient (&lt;5\u2009min) rotating behavior. The behavioral tests did not show any difference between the exposed and the control mice at any time point. Determination of ABR thresholds did not reveal an impairment of cochlea hair cells resulting from chronic B<jats:sub>0<\/jats:sub> exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Despite the transient disturbance of mice vestibular system observed immediately after B<jats:sub>0<\/jats:sub> exposure, no short\u2010term nor long\u2010term alteration was detected with behavioral and ABR tests.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.29659","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T10:20:08Z","timestamp":1681122008000},"page":"699-707","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Behavioral and functional assessment of mice inner ear after chronic exposure to an ultrahigh <scp>B<sub>0<\/sub><\/scp> field of 11.<scp>7 T<\/scp> or 17.<scp>2 T<\/scp>"],"prefix":"10.1002","volume":"90","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4767-8738","authenticated-orcid":false,"given":"Caroline","family":"Le Ster","sequence":"first","affiliation":[{"name":"University of Paris\u2010Saclay, CEA, CNRS, BAOBAB, NeuroSpin  Gif\u2010sur\u2010Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwan","family":"Selingue","sequence":"additional","affiliation":[{"name":"University of Paris\u2010Saclay, CEA, CNRS, BAOBAB, NeuroSpin  Gif\u2010sur\u2010Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosline","family":"Poirier","sequence":"additional","affiliation":[{"name":"University of Paris\u2010Saclay, CNRS, NeuroPSI  Saclay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Marc","family":"Edeline","sequence":"additional","affiliation":[{"name":"University of Paris\u2010Saclay, CNRS, NeuroPSI  Saclay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"M\u00e9riaux","sequence":"additional","affiliation":[{"name":"University of Paris\u2010Saclay, CEA, CNRS, BAOBAB, NeuroSpin  Gif\u2010sur\u2010Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2144-2484","authenticated-orcid":false,"given":"Nicolas","family":"Boulant","sequence":"additional","affiliation":[{"name":"University of Paris\u2010Saclay, CEA, CNRS, BAOBAB, NeuroSpin  Gif\u2010sur\u2010Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28131"},{"key":"e_1_2_7_3_1","unstructured":"AllardJ AmadonA AubertG et al.Progress on the commissioning of the Iseult 11.7T whole\u2010body MRI: first images. 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