{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T03:55:15Z","timestamp":1776743715662,"version":"3.51.2"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T00:00:00Z","timestamp":1697155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["18402"],"award-info":[{"award-number":["18402"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Aortic motion has direct impact on the mechanical stresses acting on the aorta. In aortic disease, increased stiffness of the aorta may lead to decreased aortic motion over time, which could be a predictor for aortic dissection or rupture. This study investigates the reproducibility of obtaining 3D displacement and diameter maps quantified using accelerated 3D cine MRI at 3\u2009T.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A noncontrast\u2010enhanced, free\u2010breathing 3D cine sequence based on balanced SSFP and pseudo\u2010spiral undersampling with high spatial isotropic resolution was developed (spatial\/temporal resolution [1.6\u2009mm]<jats:sup>3<\/jats:sup>\/67\u2009ms). The thoracic aorta of 14 healthy volunteers was prospectively scanned three times at 3\u2009T: twice on the same day and a third time 2\u2009weeks later. Aortic displacement was calculated using iterative closest point nonrigid registration of manual segmentations of the 3D aorta at end\u2010systole and mid\u2010diastole. Interexamination and interobserver regional analysis of mean displacement for five regions of interest was performed using Bland\u2013Altman analysis. Additionally, a complementary voxel\u2010by\u2010voxel analysis was done, allowing a more local inspection of the method.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences were found in mean and maximum displacement for any of the regions of interest for the interexamination and interobserver analysis. The maximum displacement measured in the lower half of the ascending aorta was 11.0\u2009\u00b1\u20093.4\u2009mm (range: 3.0\u201317.5\u2009mm) for the first scan. The smallest detectable change in mean displacement in the lower half of the ascending aorta was 3\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Detailed 3D cine balanced SSFP at 3\u2009T allows for reproducible quantification of systolic\u2013diastolic mean aortic displacement within acceptable limits.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.29856","type":"journal-article","created":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T16:45:51Z","timestamp":1697215551000},"page":"466-480","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Reproducibility of <scp>3D<\/scp> thoracic aortic displacement from <scp>3D<\/scp> cine balanced SSFP at <scp>3\u2009T<\/scp> without contrast enhancement"],"prefix":"10.1002","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0147-0939","authenticated-orcid":false,"given":"Renske","family":"Merton","sequence":"first","affiliation":[{"name":"Radiology and Nuclear Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daan","family":"Bosshardt","sequence":"additional","affiliation":[{"name":"Radiology and Nuclear Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustav J.","family":"Strijkers","sequence":"additional","affiliation":[{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"},{"name":"Biomedical Physics and Engineering Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Movement Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aart J.","family":"Nederveen","sequence":"additional","affiliation":[{"name":"Radiology and Nuclear Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"},{"name":"Amsterdam Movement Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7922-3615","authenticated-orcid":false,"given":"Eric M.","family":"Schrauben","sequence":"additional","affiliation":[{"name":"Radiology and Nuclear Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8755-0192","authenticated-orcid":false,"given":"Pim","family":"van Ooij","sequence":"additional","affiliation":[{"name":"Radiology and Nuclear Medicine Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"},{"name":"Amsterdam Cardiovascular Sciences  Amsterdam the Netherlands"},{"name":"Amsterdam Movement Sciences  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,10,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000112569.27151.F7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(98)00315-4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.702720"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-018-0891-4"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2016.05.011"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1510\/icvts.2007.166835"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-017-0733-9"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.07.045"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.08.023"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2016.11.019"},{"key":"e_1_2_8_12_1","unstructured":"MertonR SchraubenEM StrijkersGJ NederveenAJ Van OoijP.Reproducibility of aortic diameter and displacement derived from free\u2010breathing 3D balanced steady\u2010state free precession CINE images at 3T. 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