{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T17:37:38Z","timestamp":1781199458017,"version":"3.54.1"},"reference-count":44,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIH R01\u2010EB009055"],"award-info":[{"award-number":["NIH R01\u2010EB009055"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIHR01\u2010CA249893"],"award-info":[{"award-number":["NIHR01\u2010CA249893"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006775","name":"GE Healthcare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006775","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Diffusion\u2010weighted (DW) imaging provides a useful clinical contrast, but is susceptible to motion\u2010induced dephasing caused by the application of strong diffusion gradients. Phase navigators are commonly used to resolve shot\u2010to\u2010shot motion\u2010induced phase in multishot reconstructions, but poor phase estimates result in signal dropout and Apparent Diffusion Coefficient (ADC) overestimation. These artifacts are prominent in the abdomen, a region prone to involuntary cardiac and respiratory motion. To improve the robustness of DW imaging in the abdomen, region\u2010based shot rejection schemes that selectively weight regions where the shot\u2010to\u2010shot phase is poorly estimated were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Spatially varying weights for each shot, reflecting both the accuracy of the estimated phase and the degree of subvoxel dephasing, were estimated from the phase navigator magnitude images. The weighting was integrated into a multishot reconstruction using different formulations and phase navigator resolutions and tested with different phase navigator resolutions in multishot DW\u2010echo Planar Imaging acquisitions of the liver and pancreas, using conventional monopolar and velocity\u2010compensated diffusion encoding. Reconstructed images and ADC estimates were compared qualitatively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The proposed region\u2010based shot rejection reduces banding and signal dropout artifacts caused by physiological motion in the liver and pancreas. Shot rejection allows conventional monopolar diffusion encoding to achieve median ADCs in the pancreas comparable to motion\u2010compensated diffusion encoding, albeit with a greater spread of ADCs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Region\u2010based shot rejection is a linear reconstruction that improves the motion robustness of multi\u2010shot DWI and requires no sequence modifications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.30102","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T10:12:33Z","timestamp":1713262353000},"page":"519-531","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Robust multishot diffusion\u2010weighted imaging of the abdomen with region\u2010based shot rejection"],"prefix":"10.1002","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7945-902X","authenticated-orcid":false,"given":"Philip K.","family":"Lee","sequence":"first","affiliation":[{"name":"Radiology Stanford University  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2584-0558","authenticated-orcid":false,"given":"Xuetong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Radiology Stanford University  Stanford California USA"},{"name":"Bioengineering Stanford University  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian A.","family":"Hargreaves","sequence":"additional","affiliation":[{"name":"Radiology Stanford University  Stanford California USA"},{"name":"Bioengineering Stanford University  Stanford California USA"},{"name":"Electrical Engineering Stanford University  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.161.2.3763909"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.4329\/wjr.v8.i9.785"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.1695690"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2014.15.5.554"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.30067"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28846"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0730-725X(94)92539-9"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.177.2.2217777"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910230119"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21046"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910330518"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10531"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20706"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910310111"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22024"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(199911)42:5<952::AID-MRM16>3.0.CO;2-S"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10014"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.01.038"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910350518"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910380510"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.211.3.r99jn15799"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/1522-2594(200007)44:1<101::AID-MRM15>3.0.CO;2-S"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910320313"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.1880060614"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0730-725X(96)00385-2"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26382"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27488"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910170114"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910240112"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0268843"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29433"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29531"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0291273"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139839099"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2594(200005)43:5<682::AID-MRM10>3.0.CO;2-G"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26166"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24751"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1509"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.14130778"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29427"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.3390\/tomography9050146"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.08.052"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018181494"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-019-06510-3"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.30102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T20:00:51Z","timestamp":1717185651000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.30102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,16]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1002\/mrm.30102"],"URL":"https:\/\/doi.org\/10.1002\/mrm.30102","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,16]]},"assertion":[{"value":"2023-11-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-18","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}