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The purpose of this study is to determine whether aortic velocity measurements are influenced by a CIED.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We scanned 21 adult patients and 8 pediatric volunteers using clinical standard PC and real\u2010time PC (rt\u2010PC) sequences with and without a CIED generator taped on human subjects (below the left clavicle for adults and children; also on the abdomen for children) to mimic image artifacts. Peak and mean velocities above the aortic valve were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Bland\u2013Altman analyses on peak velocity measurements in pediatric subjects showed that both the accuracy and precision worsen as the distance between the CIED and aortic valve decreases (i.e., from abdomen to below the left clavicle). Specifically, both the bias and the coefficient of variation (CV) for both clinical PC and rt\u2010PC increased from the abdominal position (clinical: bias\u2009=\u2009\u22121.1%, CV\u2009=\u20094.3%; rt\u2010PC: bias\u2009=\u2009\u22120.3%, CV\u2009=\u20093.4%) to the clavicle position (clinical: bias\u2009=\u2009\u22124.0%, CV\u2009=\u20098.1%; rt\u2010PC: bias\u2009=\u20098.2%, CV\u2009=\u20097.3%). A similar trend was observed for mean velocity. The mean difference in peak and mean velocity measurements between rt\u2010PC with CIED (either position) and clinical standard PC with no CIED was within 7.5%. In adult patients, the mean difference between rt\u2010PC with CIED and clinical standard PC with CIED in peak velocity was 6.9%, and the CV was 7.9%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates that aortic velocity measurements are influenced by CIED in both adult and pediatric subjects.<\/jats:p><\/jats:sec>","DOI":"10.1002\/mrm.30399","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T17:24:54Z","timestamp":1733505894000},"page":"2099-2107","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Aortic velocity measurements derived from phase\u2010contrast <scp>MRI<\/scp> are influenced by a cardiac implantable electronic device in both adult and pediatric human subjects"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2982-6036","authenticated-orcid":false,"given":"Huili","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Radiology Northwestern University Feinberg School of Medicine  Chicago Illinois USA"},{"name":"Department of Biomedical Engineering, McCormick School of Engineering Northwestern University  Evanston Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0537-7141","authenticated-orcid":false,"given":"Oluyemi B.","family":"Aboyewa","sequence":"additional","affiliation":[{"name":"Department of Radiology Northwestern University Feinberg School of Medicine  Chicago Illinois USA"},{"name":"Department of Biomedical Engineering, McCormick School of Engineering Northwestern University  Evanston Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Webster","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Ann &amp; Robert H. Lurie Children's Hospital  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1140-314X","authenticated-orcid":false,"given":"Dhaivat","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Pediatrics Ann &amp; Robert H. 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