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Multi\u2010ROI shimming strategies were developed and implemented.  maps and in vivo images were acquired on the single transmit mode of a 7T scanner using the RF shim cases derived from the computer simulations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The availability of 60 transmit channels enables more control over  efficiency, specific absorption rate (SAR) efficiency, and  homogeneity using RF shimming. On the single transmit mode, the 2nd generation Tic Tac Toe RF coil system consistently provides homogeneous  field distribution with extended coverage into the temporal lobes, cerebellum, reaching all the way to C5\u2013C6. Safe levels of SAR are also achieved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>By using a non\u2010subject specific RF shimming approach derived from computer simulations, the 2nd generation Tic Tac Toe RF coil system allows for robust, routine neuroimaging (&gt;1750 in vivo scanning sessions over the past 28\u2009months) at 7T in single transmit mode.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.30563","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T07:35:26Z","timestamp":1747726526000},"page":"1804-1816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["<scp>RF<\/scp>\n                    shimming strategy for an open 60\u2010channel\n                    <scp>RF<\/scp>\n                    transmit\n                    <scp>7T MRI<\/scp>\n     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