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Phase\u2010cycled bSSFP\u2010based tissue phase and susceptibility maps were compared with multi\u2010echo gradient\u2010echo (MEGRE)\u2010based maps in the brains of eight healthy subjects at 7T. Additionally, , , and PD maps were obtained from the same phase\u2010cycled bSSFP data. To demonstrate the potential of matching scan time with MEGRE, bSSFP profiles were subsampled by 50% and resulting maps compared with the reference data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The tissue phase maps obtained from phase\u2010cycled bSSFP data agreed well with the reference, with a mean absolute deviation of  Hz in the entire brain of all subjects. The mean absolute deviation of tissue susceptibility was  parts\u2010per\u2010billion (ppb). Susceptibility in the globus pallidus was overestimated by 67\u2009ppb (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05), while no significant biases were observed in other regions: 3.2\u2009ppb in putamen, 15.5\u2009ppb in thalamus, and 11.9\u2009ppb in caudate nucleus (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Quantitative maps showed good contrast between different regions of the brain, aligning well with the literature. Profile subsampling did not significantly (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05) change the quantitative susceptibility maps.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The feasibility of phase\u2010cycled bSSFP for QSM at 7T was demonstrated, with the added benefit of simultaneous , , and PD mapping, with a total scan time of \u02dc20\u2009min.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.30571","type":"journal-article","created":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T01:31:13Z","timestamp":1748914273000},"page":"1469-1484","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Quantitative susceptibility mapping in the human brain at\n                    <scp>7T<\/scp>\n                    with phase\u2010cycled\n                    <scp>balanced SSFP<\/scp>"],"prefix":"10.1002","volume":"94","author":[{"given":"Berk Can","family":"Acikgoz","sequence":"first","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR) Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"},{"name":"Graduate School for Cellular and Biomedical Sciences University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Sainz Martinez","sequence":"additional","affiliation":[{"name":"CSEM \u2010 Swiss Center for Electronics and Microtechnology  Bern Switzerland"},{"name":"CIBM Center for Biomedical Imaging  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e8le L. C.","family":"Mackowiak","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR) Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"},{"name":"Department of Diagnostic and Interventional Radiology Lausanne University Hospital and University of Lausanne  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-2624-5412","authenticated-orcid":false,"given":"Nils M. J.","family":"Pl\u00e4hn","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR) Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"},{"name":"Graduate School for Cellular and Biomedical Sciences University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9573-870X","authenticated-orcid":false,"given":"Yasaman","family":"Safarkhanlo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva S.","family":"Peper","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR) Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Radojewski","sequence":"additional","affiliation":[{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"},{"name":"Department of Diagnostic and Interventional Neuroradiology University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Bonanno","sequence":"additional","affiliation":[{"name":"Department of Diagnostic, Interventional and Pediatric Radiology (DIPR) Inselspital, Bern University Hospital, University of Bern  Bern Switzerland"},{"name":"Translational Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine  Bern Switzerland"},{"name":"Department of Diagnostic and Interventional Neuroradiology University of Bern  Bern Switzerland"},{"name":"Advanced Clinical Imaging Technology Siemens Healthineers International AG  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6667-1868","authenticated-orcid":false,"given":"Jo\u00e3o","family":"Jorge","sequence":"additional","affiliation":[{"name":"CSEM \u2010 Swiss Center for Electronics and Microtechnology  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5485-1308","authenticated-orcid":false,"given":"Jessica A. 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