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DIP reconstruction was evaluated for noise and artifact reduction compared to a low\u2010rank reconstruction. Measurements were assessed in simulation and phantom for accuracy. T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      \u2010cMRF maps were generated in 10 healthy subjects and six patients under evaluation for cardiomyopathy, myocarditis, and amyloidosis receiving gadolinium\u2010based contrast agent\u2013enhanced CMR at 1.5\u2009T.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      \u2010cMRF maps showed excellent agreement with ground truth (RMS error\u2009=\u20093.0%\u2009\u00b1\u20095.3%) and conventional methods (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.99) in simulations and phantom experiments. Measured values in healthy subjects were consistent with literature (T\n                      <jats:sub>1<\/jats:sub>\n                      \u2009=\u20091051\u2009\u00b1\u200963\u2009ms, T\n                      <jats:sub>2<\/jats:sub>\n                      \u2009=\u200941.4\u2009\u00b1\u20093.3\u2009ms, and T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      \u2009=\u200945.5\u2009\u00b1\u20092.4\u2009ms). DIP reconstruction reduced noise, indicated by lower coefficient of variation (\u0394\u2009=\u20094.7), compared to low\u2010rank reconstruction. Mean differences of 10.2\u2009ms (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02) in T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      and 6.9\u2009ms in T\n                      <jats:sub>2<\/jats:sub>\n                      maps were observed between areas of enhancement on late gadolinium enhancement and normal\u2010appearing myocardium in patients. Within individual patients, significant differences (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01) in T\n                      <jats:sub>1<\/jats:sub>\n                      , T\n                      <jats:sub>2<\/jats:sub>\n                      , and T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      were observed between American Heart Association segments with and without contrast enhancement.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The proposed T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      \u2010cMRF sequence using DIP reconstruction enables simultaneous quantification of T\n                      <jats:sub>1<\/jats:sub>\n                      , T\n                      <jats:sub>2<\/jats:sub>\n                      , and T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      with decreased coefficient of variation compared to low\u2010rank reconstruction. Simulation and phantom studies show good agreement with references. In vivo measurements were made in healthy subjects, and areas of contrast enhancement in patients showed elevated T\n                      <jats:sub>2<\/jats:sub>\n                      and T\n                      <jats:sub>1\u03c1<\/jats:sub>\n                      relative to remote myocardium.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.30580","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T10:34:04Z","timestamp":1747996444000},"page":"1500-1513","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Simultaneous\n                    <scp>\n                      T\n                      <sub>1<\/sub>\n                    <\/scp>\n                    ,\n                    <scp>\n                      T\n                      <sub>2<\/sub>\n                    <\/scp>\n                    , and T\n                    <sub>1\u03c1<\/sub>\n   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