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CASPR is employed for efficient and flexible k\u2010space sampling at isotropic resolution during free breathing. The imaging pipeline includes subspace reconstruction, water\u2010fat separation, and \u2010specific dictionary matching. The proposed method was validated in a water\u2010fat relaxometry phantom using spin echo\u2010based reference techniques and was compared with MOLLI  and GRASE  mapping in 10 volunteers. The method's flexibility was assessed at isotropic resolutions of 2.5, 3, and 3.5\u2009mm, with corresponding scan times of 7:19, 5:23, and 3:52\u2009min. Additionally, the method was applied to 9 oncological patients with abdominal pathologies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Phantom experiments demonstrated good agreement between the proposed method and spin echo\u2010based reference techniques across a wide range of  and  values. The volunteer study assessed in vivo quantification performance and demonstrated the flexibility of the proposed method at different spatial resolutions. The 3\u2009mm method was successively performed in patients with abdominal pathologies, whereby lesions with diameters below 1\u2009cm could be assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The proposed Look\u2010Locker\u2010based method using CASPR enables efficient, flexible, and simultaneous  and  mapping at isotropic resolution in a fixed scan time during free breathing.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70040","type":"journal-article","created":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T06:34:56Z","timestamp":1757140496000},"page":"268-285","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Abdominal simultaneous 3D water T\n                    <sub>1<\/sub>\n                    and T\n                    <sub>2<\/sub>\n                    mapping using a free\u2010breathing Cartesian acquisition with spiral profile ordering"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3335-3331","authenticated-orcid":false,"given":"Jonathan","family":"Stelter","sequence":"first","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital Technical University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kilian","family":"Weiss","sequence":"additional","affiliation":[{"name":"Philips GmbH Market DACH  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Steinhelfer","sequence":"additional","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health, TUM University Hospital Technical University of Munich  Munich 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