{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T03:04:13Z","timestamp":1763780653377,"version":"3.45.0"},"reference-count":51,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T00:00:00Z","timestamp":1756771200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01 HL167613"],"award-info":[{"award-number":["U01 HL167613"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To determine the feasibility of tagged MRI at 0.55\u2009T and tag persistence for cardiac and speech production applications. This is particularly challenging due to the short muscle T\n                      <jats:sub>1<\/jats:sub>\n                      at 0.55\u2009T (701\u2009ms) and requires advanced techniques for maximizing initial tag contrast and signal\u2010to\u2010noise ratio (SNR)\u2013efficient imaging.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Tagged MRI was performed using phase\u2010sensitive tagging (REALTAG) two\u2010dimensional grid\u2010based preparation and spiral balanced steady\u2010state free precession (bSSFP) imaging. Experiments were performed in healthy adult volunteers using a 0.55 T MRI system with high\u2010performance gradients on two functional anatomies. Cardiac scans had 7.5\u2010mm tag spacing, 1.3\u2010mm\n                      <jats:sup>2<\/jats:sup>\n                      in\u2010plane resolution, and were acquired during about 18s breath\u2010holds. Speech scans had 10\u2010mm tag spacing, 2\u2010mm\n                      <jats:sup>2<\/jats:sup>\n                      spatial resolution, and were acquired in real time. Resulting tagged images were compared with conventional gradient\u2010recalled echo (GRE). Tag persistence and tag contrast\u2010to\u2010noise ratio were measured and compared.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>REALTAG preparation and phase\u2010sensitive reconstruction resulted in taglines that recover quickly when compared to 1.5\u2009T, for both bSSFP and GRE imaging approaches. The bSSFP approach, at optimal flip angles, provided a 1.35\u2010fold improved SNR and 1.6\u2010fold improved tag persistence. For a tag contrast\u2010to\u2010noise ratio threshold of 6, the tag persistence was about 506\u2009ms for GRE and\u2009about\u2009851\u2009ms for bSSFP.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Tagged MRI is feasible at 0.55\u2009T and can be used for functional analysis of muscle motion such as cardiac and speech applications, despite the short T\n                      <jats:sub>1<\/jats:sub>\n                      . Spiral bSSFP along with REALTAG preparation pulses provide adequate SNR and contrast to visualize cardiac systolic mechanics and to visualize tongue deformation during short speech utterances.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70060","type":"journal-article","created":{"date-parts":[[2025,9,2]],"date-time":"2025-09-02T10:01:49Z","timestamp":1756807309000},"page":"465-473","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Feasibility of tagged\n                    <scp>MRI<\/scp>\n                    at 0.55\u2009T"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0685-5160","authenticated-orcid":false,"given":"Prakash","family":"Kumar","sequence":"first","affiliation":[{"name":"Ming Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering University of Southern California   Los Angeles California 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