{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:58:55Z","timestamp":1773010735757,"version":"3.50.1"},"reference-count":46,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T00:00:00Z","timestamp":1756944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["1S24094"],"award-info":[{"award-number":["1S24094"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23TS1400300"],"award-info":[{"award-number":["23TS1400300"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82302295"],"award-info":[{"award-number":["82302295"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To develop a rapid 2D free\u2010running myocardial  mapping technique that is robust to through\u2010plane respiratory motion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A free\u2010running golden angle radial sequence consisting of  encoding and self\u2010navigated auto motion calibration (SNAC) was developed. The  encoding adopted inversion recovery (IR) prepared interleaved multi\u2010slice acquisition with optimized inter\u2010slice gap to ensure a uniform excitation of the middle slice regardless of through\u2010plane respiratory motion. The flip angles were alternated between the odd and even IR readouts to correct flip\u2010angle errors. SNAC was designed to calibrate the through\u2010plane motion with the respiratory self\u2010navigation signal extracted from the free\u2010running sequence, and integrate the multi\u2010slice data into a through\u2010plane motion\u2010corrected 2D slice for  mapping reconstruction. Numerical simulations were performed to optimize the key sequence parameters, followed by phantom and in\u2010vivo imaging to validate the accuracy and repeatability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Numerical simulations yielded the dual flip angles minimizing  estimation errors and the adjacent slice offset achieving uniformity in the superimposed slice profile. Phantom experiments demonstrated a strong correlation between the proposed and reference method, and no dependence of the free\u2010running  estimation on heart rates. Adding through\u2010plane respiratory motion correction significantly improved the in\u2010vivo  mapping sharpness and visual quality. Validated against the conventional breath\u2010hold mapping technique, the motion corrected free\u2010running method achieved comparable  mapping quality and repeatability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Respiratory motion is effectively suppressed in the proposed 2D free\u2010running method, which achieves superior  mapping with acceptable repeatability in a short scan time of 46\u00a0s.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70071","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T04:20:59Z","timestamp":1757046059000},"page":"756-769","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Rapid free\u2010breathing myocardial\n                    <i>T<\/i>\n                    <sub>1<\/sub>\n                    mapping with free\u2010running interleaved multi\u2010slice acquisition and respiratory motion correction using self\u2010navigated auto calibration"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-5176-7263","authenticated-orcid":false,"given":"Hongzhang","family":"Huang","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8917-7387","authenticated-orcid":false,"given":"Zijian","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-3456-227X","authenticated-orcid":false,"given":"Zhenfeng","family":"Lyu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-8145-699X","authenticated-orcid":false,"given":"Qinfang","family":"Miao","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genqiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Ceramics Chinese Academy of Sciences  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Hu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4709-5185","authenticated-orcid":false,"given":"Haikun","family":"Qi","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering &amp; State Key Laboratory of Advanced Medical Materials and Devices ShanghaiTech University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-017-0389-8"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.991383"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.220067"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.072"},{"key":"e_1_2_8_6_1","first-page":"1","article-title":"Histologic validation of myocardial fibrosis measured by T1 mapping: a systematic review and meta\u2010analysis","volume":"18","author":"Diao K\u2010y","year":"2017","journal-title":"J Cardiovasc Magn Reson"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2015.12.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2015150341"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2018172613"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgmr.2022.100858"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.20110"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-018-4116-x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.10.5881"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.215.2.r00ma16365"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-018-0217-y"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.833257"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28935"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27574"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2019.08.008"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27811"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29346"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29449"},{"key":"e_1_2_8_23_1","first-page":"4554","volume-title":"Comparative Analysis of Cardiac T1 Mapping Reliability: Free\u2010Breathing Versus Breath\u2010Hold Techniques","author":"Velikina JV","year":"2024"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28506"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24139"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.24977"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27681"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28580"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1117\/12.2582141"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.30317"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27763"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-017-0346-6"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.22312"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25460"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25058"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23027"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28675"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.media.2012.05.008"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27694"},{"key":"e_1_2_8_40_1","unstructured":"FesslerJA.Michigan image reconstruction toolbox.https:\/\/github.com\/JeffFessler\/mirt"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29084"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1118\/1.596622"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.25387"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.24999"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.29269"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12968-023-00973-6"},{"key":"e_1_2_8_47_1","first-page":"667","article-title":"Changes in myocardial native T1 and T2 after exercise stress: A noncontrast CMR pilot study","volume":"13","author":"Nakamori S","year":"2020","journal-title":"Cardiovasc Imaging"}],"container-title":["Magnetic Resonance in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mrm.70071","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T17:48:56Z","timestamp":1765043336000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mrm.70071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,4]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/mrm.70071"],"URL":"https:\/\/doi.org\/10.1002\/mrm.70071","archive":["Portico"],"relation":{},"ISSN":["0740-3194","1522-2594"],"issn-type":[{"value":"0740-3194","type":"print"},{"value":"1522-2594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,4]]},"assertion":[{"value":"2025-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}