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Silicone breast imaging protocols often require multiple tailored sequences for species suppression and diagnostic contrast. We propose a single sequence suitable for patients with or without implants that enables \u2010weighted, high\u2010quality imaging and three\u2010species separation within a clinically feasible scan time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Our approach uses a 2D fast spin echo (FSE) sequence with seven bipolar multi\u2010echo gradient echo readouts, enabling field mapping and water\u2013fat\u2013silicone separation. Incoherent \u2013 undersampling combined with joint multi\u2010echo reconstruction leverages temporal correlations and applies compressed sensing regularization directly to the separated species.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We achieve high\u2010resolution, artifact\u2010free water, fat, and silicone (WFS) images across three planes from one sequence, regardless of shim quality, and for different breast implant types. Compared to independent echo reconstruction and separation, joint multi\u2010echo reconstruction with incoherent \u2013 sampling allows acceleration of , reducing scan time to 2.5\u2009minutes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We demonstrate a robust \u2010weighted technique that provides reliable water\u2013fat\u2013silicone imaging in 2.5\u2009minutes, enabling uniform breast protocols for patients with and without silicone implants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70253","type":"journal-article","created":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:49:41Z","timestamp":1769093381000},"page":"2765-2775","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["T2\u2010Weighted Imaging of Water, Fat and Silicone"],"prefix":"10.1002","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9328-2155","authenticated-orcid":false,"given":"Aizada","family":"Nurdinova","sequence":"first","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2584-0558","authenticated-orcid":false,"given":"Xuetong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"},{"name":"Department of Bioengineering Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2847-8896","authenticated-orcid":false,"given":"Julio A.","family":"Oscanoa","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"},{"name":"Department of Bioengineering Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Preya","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kawin","family":"Setsompop","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"},{"name":"Department of Electrical Engineering Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce L.","family":"Daniel","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"},{"name":"Department of Bioengineering Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian A.","family":"Hargreaves","sequence":"additional","affiliation":[{"name":"Department of Radiology Stanford University  Stanford California USA"},{"name":"Department of Bioengineering Stanford University  Stanford California USA"},{"name":"Department of Electrical Engineering Stanford University  Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"\u201cPlastic Surgery Statistics Report 2020 \u201d2020."},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.210096"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1522-2586(199902)9:2<187::AID-JMRI6>3.0.CO;2-2"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002480-199407000-00074"},{"key":"e_1_2_10_6_1","volume-title":"Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM) 2012","author":"Krainak D. 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