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A closed\u2010form analytical model enables joint apparent diffusion coefficient (ADC) and T2 mapping via iterative reconstruction. The method's feasibility was evaluated via Bloch equation simulations, phantom experiments, and preliminary in vivo imaging studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Monte Carlo simulations revealed that PBD provides more accurate median ADC estimates at low signal\u2010to\u2010noise ratios (SNRs) compared to conventional single\u2010shot echo\u2010planar imaging (SS\u2010EPI), although PBD exhibited greater variability. Phantom studies demonstrated good agreement for PBD\u2010derived ADC values (e.g.,\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.99) with reference methods and strong correlation for PBD\u2010derived T2 values (e.g.,\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.89), though the latter showed some systematic bias in phantoms. In vivo results from patients with benign or malignant prostate disease demonstrated the feasibility of the PBD method to provide high\u2010resolution ADC and T2 maps with minimal geometric distortions relative to conventional SS\u2010EPI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>PBD provides ADC and T2 maps with improved geometric fidelity in phantoms and in vivo, and offers robust median ADC estimates from noisy data based on simulations. This combination of spatial precision and noise characteristics makes PBD promising for applications such as high\u2010resolution DWI for prostate MRI.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70312","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:12:36Z","timestamp":1773288756000},"page":"49-65","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Quantitative Diffusion and\n                    <scp>T2<\/scp>\n                    Mapping Using\n                    <scp>RF<\/scp>\n                    \u2010Modulated Phase\u2010Based Gradient Echo Imaging"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3615-459X","authenticated-orcid":false,"given":"Daiki","family":"Tamada","sequence":"first","affiliation":[{"name":"Department of Radiology University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Pirasteh","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Medical Physics University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David F.","family":"Jarrard","sequence":"additional","affiliation":[{"name":"Department of Urology University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Carbone Cancer Center University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0016-0317","authenticated-orcid":false,"given":"Diego","family":"Hernando","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Medical Physics University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4728-8171","authenticated-orcid":false,"given":"Scott B.","family":"Reeder","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Medical Physics University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Biomedical Engineering University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Medicine University of Wisconsin\u2010Madison  Madison Wisconsin USA"},{"name":"Department of Emergency Medicine University of Wisconsin\u2010Madison  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(02)00303-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12061493"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.rct.0000156396.13522.f2"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1593\/neo.81328"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.06.1403"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20683"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1543"},{"key":"e_1_2_10_9_1","volume-title":"Diffusion MRI of the Breast","author":"Iima M.","year":"2022"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.11098"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2007.09.016"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.01.038"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.27436"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23275"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.27492"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/nbm.1509"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.23090"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2013.12.014"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.26353"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-87615-9_1"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2020.03.007"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2016.04.015"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28138"},{"key":"e_1_2_10_24_1","volume-title":"Proceedings of the 31st Annual Meeting of ISMRM","author":"Tamada D.","year":"2022"},{"key":"e_1_2_10_25_1","unstructured":"D.Tamada D.Hernando andS. 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