{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:20:32Z","timestamp":1790364032192,"version":"4.1.0"},"reference-count":63,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:00:00Z","timestamp":1781568000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["455422993\/FOR5298\u2010iMAGO\u2010P1"],"award-info":[{"award-number":["455422993\/FOR5298\u2010iMAGO\u2010P1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>\n                      To develop a phase\u2010corrected time\u2010interleaved multi\u2010echo gradient echo Cartesian acquisition with spiral profile ordering (TIMGRECASPR) for abdominal large\u2010FOV proton density fat fraction (PDFF) mapping at 3\u2009\n                      <jats:italic>T<\/jats:italic>\n                      , demonstrating its sampling flexibility and inherent self\u2010gating capabilities at high isotropic resolutions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A methodological framework was developed to correct eddy current\u2010 and concomitant gradient\u2010related phase errors in a TIMGRECASPR acquisition. Sequence parameters were optimized with an XCAT simulation. Validation was conducted in phantoms and in vivo thigh and abdominal imaging. In five healthy volunteers, liver PDFF and\n                      <jats:italic>T2<\/jats:italic>\n                      *, alongside pancreatic PDFF, were compared to a clinical Cartesian breath\u2010hold vendor technique. Liver PDFF homogeneity was evaluated visually and across five different axial subvolumes. Mean absolute PDFF bias and within\u2010subject standard deviation (wSD) across repeated scans were quantified. Pancreatic delineation was quantified by line profiles across the tissue boundary.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Short shot lengths were required for a sufficient temporal resolution of the respiratory motion self\u2010navigation. Without phase corrections, data showed severe peripheral PDFF bias, especially at higher spatial resolutions. In a water phantom, PDFF bias ranged from \u22125% to 5% over 400\u2009mm in readout direction, successfully mitigated by the proposed phase corrections. Liver PDFF maps exhibited improved homogeneity and accurate quantification results, verified by the breath\u2010hold reference scan (0.6% PDFF bias, wSD\u2009=\u20090.11%). Pancreatic boundaries were clearly visualized and provided accurate pancreatic PDFF maps (1.1% PDFF bias, wSD\u2009=\u20090.37%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This work demonstrates the feasibility of a free\u2010breathing monopolar time\u2010interleaved gradient echo sequence based on a Cartesian spiral acquisition at 3\u2009\n                      <jats:italic>T<\/jats:italic>\n                      when accounting for phase errors.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70474","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:26:26Z","timestamp":1781677586000},"page":"1709-1725","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Free\u2010Breathing Fat Quantification Using a Phase Error\u2010Corrected Cartesian Acquisition With Spiral Profile Ordering"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4486-7776","authenticated-orcid":false,"given":"Philipp","family":"Braun","sequence":"first","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health TUM University Hospital, Technical University of Munich (TUM)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Stelter","sequence":"additional","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health TUM University Hospital, Technical University of Munich (TUM)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9658-6541","authenticated-orcid":false,"given":"Stefan","family":"Ruschke","sequence":"additional","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health TUM University Hospital, Technical University of Munich (TUM)  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes M.","family":"Peeters","sequence":"additional","affiliation":[{"name":"Philips Healthcare  Best the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger","family":"Eggers","sequence":"additional","affiliation":[{"name":"Philips GmbH Innovative Technologies  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kilian","family":"Weiss","sequence":"additional","affiliation":[{"name":"Philips GmbH Market DACH  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Junker","sequence":"additional","affiliation":[{"name":"Institute for Diagnostic and Interventional Radiology, School of Medicine and Health TUM University Hospital, Technical University of Munich (TUM)  Munich 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