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Imaging shots are followed by 2D phase navigators for phase correction of diffusion\u2010prepared shots and dummy RF pulses for T\n                      <jats:sub>2<\/jats:sub>\n                      \u2010prepared shots, as well as a constant delay to maintain the steady state of the longitudinal magnetization. Mono\u2010exponential fitting is used for ADC and T\n                      <jats:sub>2<\/jats:sub>\n                      mapping. T\n                      <jats:sub>2<\/jats:sub>\n                      mapping accuracy was assessed in a phantom against a single\u2010echo spin\u2010echo reference. In vivo, the sequence was compared in the prostate of 11 healthy volunteers against a multi\u2010echo spin\u2010echo acquisition, as well as standard and reduced FOV (rFOV) single\u2010shot EPI (ssEPI).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In the phantom experiments, T\n                      <jats:sub>2<\/jats:sub>\n                      values were not significantly different from the reference single\u2010echo spin\u2010echo measurements. ADC values in vivo were not significantly different from those obtained using ssEPI. T\n                      <jats:sub>2<\/jats:sub>\n                      values in vivo showed a mean bias of \u221221.7\u2009ms compared to those obtained using multi\u2010echo spin\u2010echo with the first echo discarded in the fitting. The proposed sequence achieved similar overall image quality scores to those of ssEPI and rFOV ssEPI, improved perceived distortion scores, but lower perceived SNR scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      The proposed approach enables 3D reduced FOV, single\u2010scan ADC, and T\n                      <jats:sub>2<\/jats:sub>\n                      mapping with mono\u2010exponential fitting in the prostate.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70510","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T17:25:28Z","timestamp":1784049928000},"page":"2292-2308","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Combined\n                    <scp>ADC<\/scp>\n                 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