{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:21:00Z","timestamp":1788153660239,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["STU.019.024"],"award-info":[{"award-number":["STU.019.024"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["101078711"],"award-info":[{"award-number":["101078711"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate single\u2010 and dual\u2010band pulse modules for suppressing extra\u2010cardiac signal in cardiac MRI, and test their applicability for time\u2010efficient imaging with reduced FOV in myocardial  mapping at 3\u2009T.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Outer Volume Suppression (OVS) was implemented using two regional saturation slabs, along the phase\u2010encoding direction. Different Amplitude\u2010Modulated (AM) and Amplitude\u2010Frequency\u2010Modulated (AM\u2010FM) pulses were explored. AM sinc and AM\u2010FM Hyperbolic Secant (HS) pulses, as single\u2010 (S:1b and HS:1b) and dual\u2010band (S:2b and HS:2b) versions, were chosen for full evaluation. Pulses were individually optimized for minimal residual signal and optimal suppression\u2010band profiles. Pulse performance was assessed through simulations and phantom experiments, and evaluated in seven healthy subjects using residual signal and quantitative myocardial  mapping with rFOV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In simulations, optimized HS pulses demonstrated superior suppression\u2010band profile homogeneity and  robustness,\u00a0while both pulse classes showed comparable  sensitivity. Phantom data revealed better signal suppression with HS pulses (S:1b: 19.22%\u2009\u00b1\u20093.23%, S:2b: 16.85%\u2009\u00b1\u20096.80%, HS:1b: 4.66%\u2009\u00b1\u20091.04%, HS:2b: 2.85%\u2009\u00b1\u20091.01%). The residual difference across slabs was slightly reduced using simultaneous dual\u2010band compared with sequential single\u2010band approaches (S:1b: 3.81% vs. S:2b: 0.92%; HS:1b: 4.56% vs. HS:2b: 0.66%). In vivo, despite significantly lower residual with HS pulses (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.0015) and visually observed artifacts with sinc pulses, no significant difference in  was observed across all configurations (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.087) in myocardial  mapping.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>AM\u2010FM pulses achieved robust suppression of extra\u2010cardiac signals, with dual\u2010band implementations minimizing suppression\u2010band differences. This can enable artifact\u2010free rFOV imaging, for improved image quality in myocardial  mapping.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70515","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T07:56:13Z","timestamp":1786002973000},"page":"2240-2252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Amplitude\u2010 and Amplitude\u2010Frequency\u2010Modulated Pulses for Outer Volume Suppression in Cardiac\n                    <scp>MRI<\/scp>\n                    : Application to Myocardial T2 Mapping"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-4111-3357","authenticated-orcid":false,"given":"Ayda","family":"Arami","sequence":"first","affiliation":[{"name":"Department of Imaging Physics Delft University of Technology  Delft the Netherlands"},{"name":"Department of Radiology Leiden University Medical 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