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However, SC ME\u2010GRE is susceptible to breathing\u2010induced field fluctuations, causing ghosting artifacts and signal loss. Recent work introduced a 1D phase navigator following the last echo to measure field variations; however, susceptibility to phase wrapping increases at longer echo times. We propose a 1D phase navigator preceding the first echo, reducing phase accumulation and eliminating the need for respiratory monitoring.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>ME\u2010GRE data covering the lower (T9\u2013T12 vertebrae) and upper (T4\u2013T8 vertebrae) thoracic SC were acquired in 20 healthy volunteers and 3 pwMS at 3T. Standard and navigator\u2010corrected images were acquired in the same acquisition. To evaluate image quality, WM and GM signal\u2010to\u2010noise ratio (SNR), WM\/GM contrast\u2010to\u2010noise ratio (CNR), and background ghosting signals were measured and compared between the two reconstructions. Both were blindly assessed for artifacts, structural delineation, and diagnostic confidence in pwMS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Navigator correction significantly increased GM and WM SNR and CNR, reduced posterior ghosting across both thoracic regions, and significantly reduced artifacts while increasing structural delineation. Preliminary evaluation in three pwMS showed consistent improvements in artifact mitigation, structural delineation, and lesion conspicuity with navigator correction, providing proof\u2010of\u2010concept for potential clinical application.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A 1D navigator prior to the first echo reduces ghosting and improves thoracic SC image quality without respiratory monitoring. This approach could improve the diagnostic value and enhance the reliability of thoracic SC ME\u2010GRE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70528","type":"journal-article","created":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T04:41:53Z","timestamp":1784954513000},"page":"2660-2674","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["<scp>1D<\/scp>\n                    Pre\u2010Acquisition Navigator Correcting Respiratory\u2010Induced Field Fluctuations in Multi\u2010Echo Gradient\u2010Echo Imaging of the Thoracic Spinal Cord"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8058-0126","authenticated-orcid":false,"given":"Alicia E.","family":"Cronin","sequence":"first","affiliation":[{"name":"Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center  Nashville Tennessee USA"},{"name":"Department of Radiology and 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