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Experiments were performed on an open, low\u2010field, field\u2010cycling MRI system using a nonuniform electromagnet. Imaging performance was assessed using a phantom and biological samples under matched total scan\u2010time conditions. RF coils with wide\u2010 and narrow\u2010bandwidth designs were evaluated to study sensitivity trade\u2010offs. Retrospective\n                      <jats:italic>k<\/jats:italic>\n                      \u2010space undersampling and compressed sensing reconstruction were applied to investigate potential scan\u2010time reduction for all acquisition strategies.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      SE\u2010SPI consistently achieved larger full width at half maximum (FWHM) values than SS\u2010TSE and MESE, indicating improved edge definition. Edge sharpness was higher along the RO (PE1) direction but comparable along the PE (PE2) direction. SS\u2010TSE provided the fastest\n                      <jats:italic>k<\/jats:italic>\n                      \u2010space acquisition and the highest central\n                      <jats:italic>k<\/jats:italic>\n                      \u2010space SNR but exhibited increased blurring and bandwidth\u2010related signal loss. MESE improved edge definition over SS\u2010TSE while requiring additional polarization cycles. SE\u2010SPI also showed greater robustness to compressed sensing undersampling.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      SE\u2010SPI provides a robust acquisition strategy for MRI in nonuniform B\n                      <jats:sub>0<\/jats:sub>\n                      field\u2010cycling systems by improving image fidelity, maintaining uniform signal intensity, enabling efficient use of high\u2010\n                      <jats:italic>Q<\/jats:italic>\n                      RF coils, and supporting compressed sensing acceleration.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70562","type":"journal-article","created":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T04:30:35Z","timestamp":1786422635000},"page":"2767-2779","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of\n                    <i>k<\/i>\n                    \u2010Space Acquisition Strategies in Nonuniform\n                    <scp>\n                      B\n                      <sub>0<\/sub>\n                    <\/scp>\n                    (\n                    <scp>NuBo<\/scp>\n                    )\n                    <scp>MRI<\/scp>"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7845-0090","authenticated-orcid":false,"given":"Yonghyun","family":"Ha","sequence":"first","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenhao","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-8705-8840","authenticated-orcid":false,"given":"Anja","family":"Samardzija","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sajad","family":"Hosseinnezhadian","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3439-5111","authenticated-orcid":false,"given":"Sebastian","family":"Theilenberg","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan","family":"Gross","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flor P.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Sun","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1416-2380","authenticated-orcid":false,"given":"Horace Z.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gigi","family":"Galiana","sequence":"additional","affiliation":[{"name":"Department of Radiology and Biomedical Imaging Yale University  New Haven Connecticut USA"},{"name":"Biomedical Engineering Yale University  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. 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