{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:04:02Z","timestamp":1790139842675,"version":"4.0.1"},"reference-count":38,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009780","name":"Region Sk\u00e5ne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011077","name":"Sk\u00e5nes universitetssjukhus","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011077","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","award":["20180510"],"award-info":[{"award-number":["20180510"]}],"id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004817","name":"Lund University Medical Faculty Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004817","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2019\u201005506"],"award-info":[{"award-number":["2019\u201005506"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011699","name":"Siemens Healthineers","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011699","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To develop and evaluate, in a feasibility study, a computationally efficient image\u2010reconstruction pipeline for 3D balanced steady state free precession (bSSFP) CINE fetal cardiac MRI that reduces radial streaking artifacts, increases effective temporal resolution, and improves diagnostic image quality compared with previous work.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Three\u2010dimensional bSSFP CINE data from 10 volunteers were used. Coil compression was performed using the region\u2010optimized virtual coils (ROVir) technique and compared with singular value decomposition (SVD) coil compression. For ROVir, the region of interest encompassed the fetal thorax, while the region of interference was positioned over the maternal subcutaneous fat to suppress unwanted signal contributions. Image reconstruction was performed for multiple temporal samplings. Two observers evaluated diagnostic image quality using a visual\u2010analog scale, and results were analyzed using visual grading characteristics (VGC). Computational efficiency was evaluated using reconstruction runtime and memory usage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Average 3D CINE acquisition time was 5\u2009min, with a reconstruction time of approximately 5\u2009h for both SVD (8channels and 8 phases) and ROVir (3 channels and 16 phases), with approximately equal memory usage. ROVir enabled higher temporal resolution by reducing the channels required. VGC analysis showed a preference for ROVir across all diagnostic criteria (AUC &gt;\u20090.5), including edge sharpness, perceived image contrast, artifact suppression, papillary muscles, great vessels, and extracardiac diagnostic image quality, with comparable median scores across temporal samplings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>ROVir coil compression improved diagnostic quality and reduced reconstruction time. By reducing memory demands, reconstruction with a higher number of cardiac phases was also possible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70590","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:19:55Z","timestamp":1790137195000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Towards Faster Fetal\n                    <scp>3D CINE<\/scp>\n                    Cardiac\n                    <scp>MRI<\/scp>\n                    Reconstruction Using Region\u2010Optimized Virtual Coils (\n                    <scp>ROVir<\/scp>\n                    )"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6458-5720","authenticated-orcid":false,"given":"Marjolein","family":"Piek","sequence":"first","affiliation":[{"name":"Clinical Physiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Clinical Physiology Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"Department of Biomedical Engineering Faculty of Engineering, Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3365-7282","authenticated-orcid":false,"given":"Johannes","family":"T\u00f6ger","sequence":"additional","affiliation":[{"name":"Clinical Physiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Clinical Physiology Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"Department of Biomedical Engineering Faculty of Engineering, Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Einar","family":"Heiberg","sequence":"additional","affiliation":[{"name":"Clinical Physiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Clinical Physiology Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"Department of Biomedical Engineering Faculty of Engineering, Lund University  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrin","family":"Fricke","sequence":"additional","affiliation":[{"name":"Pediatrics, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Pediatric Cardiology, Pediatric Heart Centre Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0041-9357","authenticated-orcid":false,"given":"Erik","family":"Hedstr\u00f6m","sequence":"additional","affiliation":[{"name":"Clinical Physiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Clinical Physiology Sk\u00e5ne University Hospital  Lund Sweden"},{"name":"Diagnostic Radiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"Department of Radiology Sk\u00e5ne University Hospital  Lund Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3786-3817","authenticated-orcid":false,"given":"Anthony H.","family":"Aletras","sequence":"additional","affiliation":[{"name":"Clinical Physiology, Department of Clinical Sciences Lund Lund University  Lund Sweden"},{"name":"School of Medicine, Laboratory of Computing, Medical Informatics and Biomedical \u2010 Imaging Technologies, Aristotle University of Thessaloniki  Thessaloniki Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,22]]},"reference":[{"issue":"21","key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1016\/j.jacc.2011.08.025","article-title":"Birth Prevalence of Congenital Heart Disease Worldwide: A Systematic Review and Meta\u2010Analysis","volume":"58","author":"Van Der Linde D.","year":"2011","journal-title":"Journal of the American College of Cardiology"},{"issue":"5","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s00246-010-9648-2","article-title":"The Impact of Prenatal Diagnosis of Complex Congenital Heart Disease on Neonatal Outcomes","volume":"31","author":"Levey A.","year":"2010","journal-title":"Pediatric Cardiology"},{"issue":"6","key":"e_1_2_10_4_1","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1046\/j.1442-200x.1999.01154.x","article-title":"Has Fetal Echocardiography Improved the Prognosis of Congenital Heart Disease? 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