{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:55:41Z","timestamp":1790927741721,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:00:00Z","timestamp":1790899200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009400","name":"Medizinische Fakult\u00e4t, Heinrich-Heine-Universit\u00e4t D\u00fcsseldorf","doi-asserted-by":"publisher","award":["2024\u201007"],"award-info":[{"award-number":["2024\u201007"]}],"id":[{"id":"10.13039\/501100009400","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Magnetic Resonance in Med"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to assess the feasibility of QSM in the human kidney during free\u2010breathing using respiratory gating for motion compensation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Renal imaging of 15 healthy volunteers was performed using an axial multi\u2010echo GRE sequence on a 3\u2009T MRI scanner. Each subject was scanned once during breath\u2010hold and once during free\u2010breathing with respiratory gating based on a respiratory cushion. Five subjects were repositioned and scanned again to test for reproducibility. Additionally, one subject was measured in axial and coronal direction maximizing the feasible resolution during free\u2010breathing. All phase data was unwrapped, the background field removed, and the inverse problem solved to create susceptibility maps. For statistical analysis, the mean susceptibility values of one kidney were analyzed across three consecutive slices and referenced to the susceptibility of the paravertebral muscle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The investigation revealed no statistically significant differences between the breath\u2010hold and respiratory gated sequence. The mean susceptibility values recorded in the right kidney were  for the breath\u2010hold and  for the free\u2010breathing. Bland\u2013Altman analysis demonstrated good reproducibility for both methods. The high\u2010resolution measurements enabled by gated breathing showed renal detail previously unseen in QSM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Free\u2010breathing QSM protocols in the human kidney using respiratory gating show equal susceptibility results compared to breath\u2010hold acquisition while increasing clinical feasibility. A free\u2010breathing protocol allows for the measurement of a larger subject pool and enables an increase in critical sequence parameters, such as echo\u2010time and resolution. This could improve the accuracy of susceptibility calculations in the human abdomen.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mrm.70604","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:28:07Z","timestamp":1790926087000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["From Breath\u2010Hold to Free\u2010Breathing: Possibilities in High\u2010Resolution Quantitative Susceptibility Mapping (\n                    <scp>QSM<\/scp>\n                    ) of the Kidney With Respiratory Gating"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8243-1558","authenticated-orcid":false,"given":"Matthias","family":"Deitermann","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Medical Faculty and University Hospital D\u00fcsseldorf, Heinrich\u2010Heine\u2010University D\u00fcsseldorf  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