{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T23:48:52Z","timestamp":1790034532158,"version":"4.0.1"},"reference-count":49,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T00:00:00Z","timestamp":1336694400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2012,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Subjective reports of sleep dysfunction are common in people with rheumatoid arthritis (RA). Our objective was to determine whether excess sleepiness in RA is associated with polysomnographic (PSG) abnormalities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twelve RA participants with abnormal sleep scores were identified in clinic and age\/gender matched to RA participants with normal Epworth Sleepiness Scale (ESS) scores. A total of 25 participants were recruited. All participants underwent overnight PSG studies with measurement of apnoea\u2013hypopnoea indexes (AHI). Questionnaire instruments, including the ESS, Berlin questionnaire for sleep apnoea risk, visual analogue scale for fatigue, modified Health Assessment Questionnaire (mHAQ) and the Center for Epidemiologic Studies \u2013 Depression (CES\u2010D) score, along with RA assessments, were reapplied on the PSG study night.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven men and 18 women participated. Ten participants had abnormal ESS scores and 15 had normal ESS scores on the PSG night. PSG data revealed that 68% of patients had abnormal AHI (\u2265 5). Abnormal ESS (&gt; 10) had an 80% positive predictive value (PPV) for abnormal AHI; the negative predictive value (NPV) of normal ESS was 40%. By contrast, high\u2010risk categorization for obstructive sleep apnoea (OSA) by the Berlin questionnaire had a PPV of 77.8%, and for low\u2010risk status, an NPV of 37.5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the present study population, there was a high prevalence of abnormal AHI consistent with OSA. An abnormal ESS had high positive predictive value for an abnormal AHI. Copyright \u00a9 2012 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.1016","type":"journal-article","created":{"date-parts":[[2012,5,11]],"date-time":"2012-05-11T11:01:18Z","timestamp":1336734078000},"page":"187-195","source":"Crossref","is-referenced-by-count":28,"title":["Do Sleepy Rheumatoid Arthritis Patients Have A Sleep Disorder?"],"prefix":"10.1002","volume":"10","author":[{"given":"John A.","family":"Gjevre","sequence":"first","affiliation":[{"name":"University of Saskatchewan  Saskatoon SK Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina M.","family":"Taylor\u2010Gjevre","sequence":"additional","affiliation":[{"name":"University of Saskatchewan  Saskatoon SK Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bindu V.","family":"Nair","sequence":"additional","affiliation":[{"name":"University of Saskatchewan  Saskatoon SK Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun J.","family":"Lim","sequence":"additional","affiliation":[{"name":"University of Saskatchewan  Saskatoon SK Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,5,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2007.09.001"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1389-9457(03)00010-8"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.5.667"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27351"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(89)90047-4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.311.7013.1145"},{"key":"e_1_2_6_8_1","volume-title":"Principles and Practice of Sleep Medicine (3rd edn)","author":"Carskadon MA","year":"2000"},{"key":"e_1_2_6_9_1","first-page":"1011","article-title":"Pain sensitivity in sleepy pain\u2010free normals","volume":"32","author":"Chhangani BS","year":"2009","journal-title":"Sleep"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/msc.155"},{"key":"e_1_2_6_11_1","volume-title":"Biostatistics. A Foundation for Analysis in the Health Sciences","author":"Daniel WW","year":"1999"},{"key":"e_1_2_6_12_1","first-page":"245","article-title":"Obstructive sleep apnea associated with adult\u2010acquired micrognathia from rheumatoid arthritis","volume":"127","author":"Davies SF","year":"1983","journal-title":"American Review of Respiratory Diseases"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/39.11.1287"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/37.1.71"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.5664\/jcsm.26347","article-title":"Menopause related sleep disorders","volume":"1","author":"Eichling PS","year":"2005","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e3181fe365a"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/39.3.321"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/msc.174"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780370107"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2004.01.001"},{"key":"e_1_2_6_21_1","volume-title":"The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications","author":"Iber C","year":"2007"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/14.6.540"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780340605"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000219721.89552.51"},{"key":"e_1_2_6_25_1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.5664\/jcsm.28041","article-title":"Sleep quality and functional disability in patients with rheumatoid arthritis","volume":"7","author":"Luyster FS","year":"2011","journal-title":"Journal of Clinical Sleep Medicine"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/anr.1780320806"},{"key":"e_1_2_6_27_1","first-page":"S89","article-title":"Sleep misperception in patients with rheumatoid arthritis","volume":"6","author":"Mahowald ML","year":"2005","journal-title":"Sleep Medicine"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e328333b9cc"},{"key":"e_1_2_6_29_1","volume-title":"Principles and Practice of Sleep Medicine (3rd edn)","author":"Montplaisir J","year":"2000"},{"key":"e_1_2_6_30_1","first-page":"340","article-title":"Night to night variability in sleep apnea and sleep\u2010related periodic movements in the elderly","volume":"11","author":"Mosko SS","year":"1988","journal-title":"Sleep"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.085464"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-131-7-199910050-00002"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.14a30.x"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780261107"},{"key":"e_1_2_6_35_1","first-page":"307","article-title":"The association between daytime sleepiness and sleep\u2010disordered breathing in NREM and REM sleep","volume":"25","author":"Punjabi NM","year":"2002","journal-title":"Sleep"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/014662167700100306"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.081335"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009748809098796"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2010.02.010"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-009-0975-z"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.2217\/ijr.11.6"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0b013e3181eeb2df"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/msc.208"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X11416862"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/23.1.1d"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(98)00081-X"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.069690"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.090362"},{"key":"e_1_2_6_49_1","first-page":"1942","article-title":"Sleep disturbance in patients with rheumatoid arthritis: Evaluation by medical outcomes study and visual analog sleep scales","volume":"33","author":"Wolfe F","year":"2006","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.007831"}],"container-title":["Musculoskeletal Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmsc.1016","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmsc.1016","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/msc.1016","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T19:49:01Z","timestamp":1697485741000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/msc.1016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,11]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["10.1002\/msc.1016"],"URL":"https:\/\/doi.org\/10.1002\/msc.1016","archive":["Portico"],"relation":{},"ISSN":["1478-2189","1557-0681"],"issn-type":[{"value":"1478-2189","type":"print"},{"value":"1557-0681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,11]]}}}