{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T11:42:52Z","timestamp":1777290172527,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,19]],"date-time":"2014-02-19T00:00:00Z","timestamp":1392768000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Exercise has traditionally been an important part of the treatment of ankylosing spondylitis (AS) in order to maintain spinal mobility. Additionally, anti\u2010tumour necrosis factor\u2010alpha (TNF\u03b1) medication has been proven highly effective in treating the condition. Over recent years, a few papers have shown the synergistic effect of combining anti\u2010TNF\u03b1 medication with rehabilitation. There is minimal evidence on the perceptions of AS patients on how the medication has affected their exercise behaviour. The aim of the present study was to explore the effects of anti\u2010TNF\u03b1 medication on exercise behaviour in patients with AS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>A qualitative approach was adopted to provide a holistic understanding of participants\u2019 exercise behaviour while on anti\u2010TNF\u03b1 medication. Semi\u2010structured interviews were undertaken and transcribed verbatim. Data were analysed using thematic network analysis. Ethical approval and informed consent were obtained.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty participants (age range 26\u201374, disease duration 3\u201336 years) who had been on the medication for over a year described how their exercise behaviour had improved since being on the medication. They highlighted their motivation and incentives to continue with an exercise programme. The participants had reinstated previous sporting activities, started new ones and regularly undertook physiotherapy exercises.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present study provides evidence of the long\u2010term effects of anti\u2010TNF\u03b1 medication on the exercise behaviour of AS patients. It shows that AS patients are able to sustain a regular exercise programme over a number of years, provides insight into what motivates them to exercise and reveals the incentives that have influenced their choice of activity. Copyright \u00a9 2014 John Wiley &amp; Sons, Ltd.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.1068","type":"journal-article","created":{"date-parts":[[2014,2,20]],"date-time":"2014-02-20T06:20:40Z","timestamp":1392877240000},"page":"150-159","source":"Crossref","is-referenced-by-count":8,"title":["An Exploration of the Impact of Anti\u2010TNF\u03b1 Medication on Exercise Behaviour in Patients with Ankylosing Spondylitis"],"prefix":"10.1002","volume":"12","author":[{"given":"Jennifer","family":"Stockdale","sequence":"first","affiliation":[{"name":"Blackpool Teaching Hospital NHS Foundation Trust  Blackpool UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Selfe","sequence":"additional","affiliation":[{"name":"School of Sports, Tourism and the Outdoors University of Central Lancashire  Preston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazel","family":"Roddam","sequence":"additional","affiliation":[{"name":"School of Sports, Tourism and the Outdoors University of Central Lancashire  Preston UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,19]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/146879410100100307"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5606\/tjr.2011.015"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-011-2147-9"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/039463200902200430"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.078139"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken191"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3282fa13c9"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1053\/apmr.2003.50013"},{"key":"e_1_2_6_10_1","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1093\/ptj\/86.7.924","article-title":"Effects of a multimodal exercise program for people with ankylosing spondylitis","volume":"86","author":"Ince G","year":"2006","journal-title":"Physical Therapy"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-007-0765-0"},{"key":"e_1_2_6_12_1","first-page":"2029","article-title":"Effects of a combination treatment of an intensive rehabilitation program and etanercept in patients with ankylosing spondylitis: A pilot study","volume":"33","author":"Lubrano E","year":"2006","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.110362"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.022582"},{"key":"e_1_2_6_15_1","unstructured":"National Institute for Health and Clinical Excellence (NICE)(2008).Adalimumab etanercept and infliximab for ankylosing spondylitis. 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