{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:15:21Z","timestamp":1787242521856,"version":"build-2736575974"},"reference-count":73,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Patients with systemic sclerosis (SSc) experience reduced exercise capacity and muscle strength compared with healthy subjects. There are also indications of reduced levels of physical activity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To present the current knowledge of physical exercise in SSc.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most studies presently available [three case studies, one single subject experimental design, one study comparing patients with healthy controls, one quasi experimental design (pre\u2013post), two clinical trials and two random controlled trials] have included small samples of patients, mostly composed of patients with and without pulmonary involvement. It seems that patients with SSc without pulmonary involvement are able to perform and benefit from aerobic exercises of at least moderate intensity. Exercise tolerance, aerobic capacity, walking distance, muscle strength and muscle function as well as health\u2010related quality of life (HRQL) have been found to be improved after participation in programmes including aerobic exercise and aerobic exercise combined with resistance exercises. Improvements seem to be only partially retained at follow up. Patients with pulmonary involvement may also experience improved muscle strength, physical and aerobic capacity, as well as HRQL following exercise.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with SSc without pulmonary involvement can be recommended to be as physically active as the general population. Patients with mild pulmonary involvement can be recommended to be physically active by engaging in exercises of moderate intensity and to participate in moderate\u2010load resistance exercises. Health professionals should inform patients with SSc about the importance of physical activity and avoidance of a sedentary lifestyle.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/msc.1185","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T15:33:34Z","timestamp":1491406414000},"page":"316-323","source":"Crossref","is-referenced-by-count":30,"title":["Aerobic and resistance exercise in systemic sclerosis: State of the art"],"prefix":"10.1002","volume":"15","author":[{"given":"Nat\u00e1lia Cristina","family":"de Oliveira","sequence":"first","affiliation":[{"name":"Research Group in Physical Exercise, Lifestyle and Health Promotion. Health Promotion Master Program UNASP \u2010 Adventist University of S\u00e3o Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie Andrews","family":"Portes","sequence":"additional","affiliation":[{"name":"Research Group in Physical Exercise, Lifestyle and Health Promotion. Health Promotion Master Program UNASP \u2010 Adventist University of S\u00e3o Paulo  S\u00e3o Paulo SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Pettersson","sequence":"additional","affiliation":[{"name":"Unit of Rheumatology, Department of Medicine Solna, Karolinska Institutet, and, Functional Area Occupational Therapy &amp; Physiotherapy, Allied Health Professionals Function Karolinska University Hospital, and, Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene","family":"Alexanderson","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, and, Functional Area Occupational Therapy &amp; Physiotherapy, Allied Health Professionals Function Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carina","family":"Bostr\u00f6m","sequence":"additional","affiliation":[{"name":"Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, and, Functional Area Occupational Therapy &amp; Physiotherapy, Allied Health Professionals Function Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,5]]},"reference":[{"issue":"3","key":"e_1_2_7_2_1","first-page":"S5","article-title":"Assessment of skin, joint, tendon and muscle involvement","volume":"21","author":"Akesson A.","year":"2003","journal-title":"Clinical and Experimental Rheumatology"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-86"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21715"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12566"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2015.07.012"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-008-1006-x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.136929"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.091165"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e32834ff2e8"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12299"},{"issue":"2","key":"e_1_2_7_12_1","first-page":"86","article-title":"Exercise as an anti\u2010inflammatory therapy for rheumatic diseases \u2013 Myokine regulation. Nature Reviews","volume":"11","author":"Benatti F. B.","year":"2015","journal-title":"Rheumatology"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2007.070367"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(83)90004-5"},{"key":"e_1_2_7_15_1","first-page":"141","volume-title":"Physical activity in rheumatic diseases (In Swedish)","author":"Bostr\u00f6m C.","year":"2014"},{"issue":"2","key":"e_1_2_7_16_1","first-page":"E114","article-title":"Oral complaints in progressive systemic sclerosis: Two cases report","volume":"13","author":"Cazal C.","year":"2008","journal-title":"Medicina Oral, Patolog\u00eda Oral y Cirug\u00eda Bucal"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.06.033"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2013.06.025"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu133"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780210111"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009740903555358"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740701605889"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.10.020"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009740903124416"},{"issue":"8","key":"e_1_2_7_25_1","first-page":"961","article-title":"Systemic sclerosis\/scleroderma: A treatable multisystem disease","volume":"78","author":"Hinchcliff M.","year":"2008","journal-title":"American Family Physician"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.30071"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24676"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20787"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2015.1019962"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.096677"},{"issue":"7","key":"e_1_2_7_31_1","first-page":"1573","article-title":"Criteria for the classification of early systemic sclerosis","volume":"28","author":"LeRoy E. C.","year":"2001","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1590\/bjpt-rbf.2014.0084"},{"issue":"3","key":"e_1_2_7_33_1","first-page":"44","article-title":"Efficacy of a tailored rehabilitation program for systemic sclerosis","volume":"27","author":"Maddali Bongi S.","year":"2009","journal-title":"Clinical and Experimental Rheumatology"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-010-1382-9"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027993"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jht.2008.06.009"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/1479972309348654"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37988"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/030097400750041389"},{"key":"e_1_2_7_40_1","first-page":"53","article-title":"Reduced hypoxia risk in a systemic sclerosis patient with interstitial lung disease after long\u2010term pulmonary rehabilitation. Clinical Medical Insights","volume":"4","author":"Mugii N.","year":"2011","journal-title":"Case Report"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(84)90309-8"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090484"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200508-1211ST"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4267"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09861.x"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1224180"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130032"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2003.tb00413.x"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.06.007"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2017.1281436"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.130912"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e3181d6858b"},{"key":"e_1_2_7_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-003-0216-5"},{"key":"e_1_2_7_54_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e328335a7d2"},{"key":"e_1_2_7_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-013-2282-7"},{"key":"e_1_2_7_56_1","article-title":"A personalized physical therapy program or usual care for patients with systemic sclerosis: A randomized controlled trial","author":"Rannou F.","year":"2016","journal-title":"Arthritis Care and Research"},{"issue":"6","key":"e_1_2_7_57_1","first-page":"S103","article-title":"Exercise tolerance in systemic sclerosis patients without pulmonary impairment: Correlation with clinical variables","volume":"32","author":"Rosato E.","year":"2014","journal-title":"Clinical and Experimental Rheumatology"},{"key":"e_1_2_7_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27695"},{"key":"e_1_2_7_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20448"},{"key":"e_1_2_7_60_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.110.6.1520"},{"issue":"4","key":"e_1_2_7_61_1","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/01823246-200920040-00003","article-title":"Exercise training in patients with pulmonary arterial hypertension: A case report","volume":"20","author":"Shoemaker M. J.","year":"2009","journal-title":"Cardiopulmonary Physical Therapy Journal"},{"key":"e_1_2_7_62_1","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02452"},{"key":"e_1_2_7_63_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.148767"},{"key":"e_1_2_7_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2007.12.001"},{"key":"e_1_2_7_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90311-C"},{"key":"e_1_2_7_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/echo.12690"},{"key":"e_1_2_7_67_1","unstructured":"The Swedish National Board of Health and Welfare. (2016).Systemisk skleros. Retrieved fromhttp:\/\/www.socialstyrelsen.se\/ovanligadiagnoser\/sklerodermi. [cited: 23 June 2016]."},{"key":"e_1_2_7_68_1","unstructured":"The Swedish Scleroderma Study Group. (2015).V\u00e5rdprogram f\u00f6r sklerodermi\/systemisk skleros. Retrieved fromhttp:\/\/www.svenskreumatologi.se\/sites\/default\/files\/8\/images\/sklerodermi_2010.pdf. [cited: 23 June 2016]."},{"key":"e_1_2_7_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3280147107"},{"key":"e_1_2_7_70_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-0630"},{"key":"e_1_2_7_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.02.042"},{"key":"e_1_2_7_72_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2006.062901"},{"key":"e_1_2_7_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22595"},{"key":"e_1_2_7_74_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.5.1637"}],"container-title":["Musculoskeletal Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmsc.1185","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/msc.1185","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T11:56:34Z","timestamp":1695729394000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/msc.1185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,5]]},"references-count":73,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1002\/msc.1185"],"URL":"https:\/\/doi.org\/10.1002\/msc.1185","archive":["Portico"],"relation":{},"ISSN":["1478-2189","1557-0681"],"issn-type":[{"value":"1478-2189","type":"print"},{"value":"1557-0681","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,5]]}}}