{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:33:35Z","timestamp":1790631215805,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T00:00:00Z","timestamp":1698710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Musculoskeletal Care"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The Hip Injection Trial (HIT) compared the effectiveness of adding a single ultrasound\u2010guided intra\u2010articular injection of either corticosteroid and local anaesthetic or local anaesthetic alone to advice and education among people with hip osteoarthritis (OA). This nested qualitative study explored participants' experiences of living with hip OA and of the trial treatment they received.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Semi\u2010structured telephone interviews were undertaken with a purposeful sample of trial participants after a 2\u2010month trial follow\u2010up. Interviewers were blinded to which injection participants had received. Thematic analysis using constant comparison was undertaken prior to knowing the trial results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>34 trial participants were interviewed across all arms. OA causes pain, physical limitations, difficulties at work, lowered mood, and disrupted sleep. Those who received advice and education alone felt that they had not received \u2018treatment\u2019 and described little\/no benefit. Participants in both injection groups described marked improvements in pain, physical function, and other aspects of life (e.g., sleep, confidence). The perceived magnitude of benefit appeared greater among those who received the corticosteroid injection; however, the length of benefit varied in both injection groups. There was uncertainty about the longer\u2010term benefits of injection and repeated injections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Hip OA is highly burdensome. Participants perceived little\/no benefit from advice and education alone but reported marked improvements when combined with either injection. However, the magnitude of benefit was greater among those who received corticosteroid. The varying duration of response to injection and uncertainty regarding longer\u2010term benefits of injection and repeated injections suggests that these areas are important for future research.<\/jats:p><jats:p><jats:bold>Trial registration:<\/jats:bold> EudraCT 2014\u2010003412\u201037; ISRCTN50550256.<\/jats:p><\/jats:sec>","DOI":"10.1002\/msc.1830","type":"journal-article","created":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T13:11:45Z","timestamp":1698757905000},"page":"1601-1611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Experiences of living with hip osteoarthritis and of receiving advice, education and ultrasound\u2010guided intra\u2010articular hip injection in the hip injection trial. A qualitative study"],"prefix":"10.1002","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0374-2862","authenticated-orcid":false,"given":"Melanie Ann","family":"Holden","sequence":"first","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Hawarden","sequence":"additional","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"},{"name":"Haywood Academic Rheumatology Centre Midlands Partnership NHS Foundation Trust  Stoke\u2010on\u2010Trent UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoe","family":"Paskins","sequence":"additional","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"},{"name":"Haywood Academic Rheumatology Centre Midlands Partnership NHS Foundation Trust  Stoke\u2010on\u2010Trent UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Roddy","sequence":"additional","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"},{"name":"Haywood Academic Rheumatology Centre Midlands Partnership NHS Foundation Trust  Stoke\u2010on\u2010Trent UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian D.","family":"Mallen","sequence":"additional","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Liddle","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute Newcastle University  Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Bourton","sequence":"additional","affiliation":[{"name":"Centre for Academic Primary Care Lifespan and Population Health School of Medicine University of Nottingham  Nottingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clare","family":"Jinks","sequence":"additional","affiliation":[{"name":"Primary Care Centre Versus Arthritis School of Medicine Keele University  Keele UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"HIT trial team","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,31]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2019.06.011"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.16.2.509"},{"key":"e_1_2_10_4_1","unstructured":"Charmaz K.(2006).Constructing grounded theory: A practical guide through qualitative research."},{"key":"e_1_2_10_5_1","volume-title":"Analysing qualitative data in psychology","author":"Clark V.","year":"2016"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063\u2010018\u20102983\u2010y"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2014.06.002"},{"key":"e_1_2_10_8_1","volume-title":"Developing and evaluating complex interventions: New guidance","author":"Craig P.","year":"2008"},{"key":"e_1_2_10_9_1","volume-title":"Qualitative inquiry and research design: Choosing among five approaches","author":"Creswell J.","year":"2007"},{"issue":"1","key":"e_1_2_10_10_1","first-page":"1","article-title":"How interpretive qualitative research extends mixed methods research","volume":"13","author":"Creswell J. 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